摘要
目的比较内镜经黏膜下隧道肿瘤切除术(submucosal tunnelling endoscopic resection,STER)与内镜黏膜下肿物挖除术(endoscopic submucosal excavation,ESE)治疗食管下段及食管胃连接处(esophagogastric junction,EGJ)黏膜下肿物的疗效及安全性。方法 2015年7月至2016年12月,武汉大学人民医院内镜中心共对23例发现食管下段及EGJ黏膜下肿物患者进行了STER治疗,选取同时段23例行ESE的病例作为对照组。回顾性分析其临床资料,对比分析两组的手术特点及术后并发症情况。结果两组患者黏膜下肿物均完全切除,STER组肿物面积、肿物直径均较ESE组更大,但STER组术后住院时间较ESE组更短,肿物单位面积手术费用较ESE组低,差异均有统计学意义(P<0.05)。STER组患者中有1例患者出现纵膈积气及术后发热,ESE组中有1例患者出现术后发热,均经保守治疗后好转。两组患者均无术后迟发型出血、穿孔、局部病灶复发。结论 STER相较ESE在治疗食管下段及EGJ部黏膜下肿物更加经济和高效。
Objective To compare the curative effect of submucosal tunnelling endoscopic resection(STER)and endoscopic submucosal excavation(ESE)on submucosal tumors of lower esophagus and esophagogastric junction(EGJ).Methods Twenty-three patients with submucosal tumors of lower esophagus and EGJ who underwent the STER were selected.Twenty-three patients who underwent the ESE were selected as controls in the same period.Results All lesions in 46 patients were successfully resected without surgical procedures.The average tumor area and size in STER were bigger than those in ESE.The average time in hospital after operation of STER was shorter than that in ESE.While the expense of STER in per square centimeter was cheaper than that in ESE.One patient in STER developed air leakage in mediastinum which was then absorbed.One patient in ESE had a fever and then improved after treatment.No delayed hemorrhage after operation,per foration and local lesion recurrence occurred in STER and ESE.Conclusion STER is a more economical and effective treatment for submucosal tumors than ESE.
作者
曾西
陈明锴
吴楠楠
王芳
ZENG Xi;CHEN Mingkai;WU Nannan;WANG Fang(Department of Gastroenterology,Renmin Hospital of Wuhan University,Wuhan 430060,China)
出处
《胃肠病学和肝病学杂志》
CAS
2018年第4期418-421,共4页
Chinese Journal of Gastroenterology and Hepatology
