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单抗导向超抗原SEA的抗肿瘤作用 被引量:1

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作者 韦跃宇
出处 《杭州医学高等专科学校学报》 2002年第5期229-231,共3页 Journal of Hangzhou Medical College
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参考文献10

  • 1许桂莲,朱锡华,杨劲.超抗原SEA对外周血T细胞的活化作用[J].免疫学杂志,2001,17(2):85-87. 被引量:8
  • 2[2]Rosendahl A, Kristensson K, Hansson J, et al. Perforin and IFN-gamma are involved in the antitumor effects of antibody-Targeted superantigens[J]. Immunol ,1998,160(11):5309-13.
  • 3[3]Holzer U, Orlikowsky T, Zehrer C, et al. T-cell stimulation and cytokinerel ease induced by staphylococcal enterotoxin A(SEA) and the SEAD227A mutant[J] . Immunology 1997,90 (1):47-80.
  • 4[4]Newton D W, Dohlsten M, Lando P A, et al. MHC class Ⅱ-independent, Vbeta-s pecific activation of T cells by superantigen Mutants fused to anti-tumor Fab fragments:implications for use in treatment of human colon carcinoma[J].Int J Mol med 1998,1(1):175-62.
  • 5[5]Litton M J, Dohlsten M, Lando P A, et al. Antibody-targeted superantigen the rapy induces tumor-infiltrating lymphocytes Excessive cytokine production and a poptosis in human colon carcinoma[J]. Eur J Immunol, 1996,26(1):1.
  • 6[6]Litton M J, Dohlsten M, Rosendahl A, et al .The distinct role of CD4+ and CD 8+ T-cell during the anti-tummour effects Of targeted superantigens[J]. Br J Cancer. 1999,81 (2):359-6.
  • 7[7]Rosendahl A, Kristensson K, Hansson J, et al.Repeated treatment with antibody-targeted superantigens strongly inhibits tumor growth[J]. Int J Cancer,1998,13,76(2):274-83.
  • 8[8]Giantonio B J, Ajpaugh R K, Schult J, et al. Superantigen-based immunotherapy A phase Ⅰ ccial of PNV-215465, a monoc-lonal antibody-staphylococcal enter otoxin A recombirant fasion protein in advanced pancreatic and colorected cancer[J]. J Clin Opcol,1997,15(5):1994.
  • 9王青青,余海,鱼达.C_(215)抗原基因转染的瘤苗联合单抗与超抗原的融合蛋白C_(215)Fab-SEA的抗肿瘤作用初步研究[J].中国免疫学杂志,2001,17(2):76-77. 被引量:5
  • 10[10]Haras S, Nagai H, Miyake H, et al .Secreted type of modified interleukin-18 gene transduced into mouse renal cell carcinoma cells induces systemic tumor immunity[J].2001,165:2039-43.

二级参考文献9

  • 1Zhao Y X,Immunology,1997年,92卷,2期,188页
  • 2Terje Kalland,Mikael Dohlsten,Lars Abrahmsén,Gunnar Hedlund,Per Bj?rk,Peter A. Lando,Anette Sundstedt,Eva ?kerblom,Peter Lind.Targeting of superantigens[J].Cell Biophysics (-).1993(1-3)
  • 3KallandT.Staphylococcalenterotoxin dependentcell mediatedcytotoxicity[].CurrTopicsMicrobiolImmunol.1991
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  • 9Litton MJ,Dohlsten M,Lando PA,et al.Antibody-targeted superantigen therapy induces tumor infiltrating lymphocytes excessive cytokines production and apoptosis in human colon carcinoma[].European Journal of Immunology.1996

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