摘要
目的分析慢性乙型肝炎(CHB)患者焦虑和抑郁情绪以及应对方式对患者出院后生活质量的影响。方法 2015年6月~2016年12月在我院治疗的CHB患者75例,另选同期体检的健康人70例作为对照组。采用焦虑自评量表(SAS)、抑郁自评量表(SDS)、特质应对方式问卷(TCSQ)和世界卫生组织生活质量测定简表(WHOQOL-BREF)对两组人群进行评分,采用多元回归分析SAS评分、SDS评分、TCSQ评分对患者生活质量的影响。结果 CHB患者SAS得分为(66.8±9.5)分、SDS得分为(64.5±10.2)分、TCSQ中消极应对(NC)得分为(38.3±9.6)分,均显著高于健康人[分别为(37.9±8.4)分、(41.3±9.1)分和(23.1±6.4)分,P<0.05];CHB患者积极应对(PC)得分为(26.4±8.1)分,HOQOL-BREF总分为(65.7±14.3)分,均显著低于健康人[分别为(23.1±6.4)分和(78.4±8.2)分,P<0.05];经Pearson相关分析,结果显示WHOQOL-BREF生活质量中的生理和心理领域得分与SAS评分、SDS评分、TCSQ评分中的PC和NC因子之间均存在相关性(P<0.05或P<0.01),多元线性回归分析结果表明,SDS、PC和NC评分是CHB患者生活质量中生理领域的影响因子,而PC评分是CHB患者心理领域的影响因子(均P<0.01)。结论慢性乙型肝炎患者的生活质量较正常人明显降低,尤其是在生理和心理领域,其生活质量与焦虑和抑郁情绪及积极应对方式有关。
Objective To investigate the changes of emotion,attitude and quality of life in patients with chronic hepatitis B(CHB).Methods 75 patients with CHB and 70 healthy persons were recruited in our hospital between June 2015 and December 2016.The self rating anxiety scale(SAS),self rating depression scale(SDS)and trait coping style questionnaire(TCSQ)and quality of life scale by WHO(WHOQOL-BREF)were obtained in the two groups.Logistic analysis was applied to evaluate the impact of them on the quality of life in patients with CHB.Results The SAS score,SDS score and the negative score of TCSQ in patients with CHB were(66.8±9.5),(64.5±10.2)and(38.3±9.6),respectively,much higher than[(37.9±8.4),(41.3±9.1)and(23.1±6.4),P<0.05]in the control;the positive score of TCSQ in patients with CHB was(26.4±8.1),and HOQOL-BREF score was(65.7±14.3),much lower than[(23.1±6.4)and(78.4±8.2),P<0.05]in the control;the physical and psychological score of WHOQOL-BREF in patients with CHB were positively correlated to positive score and negative score of SAS,SDS and TCSQ(P<0.05 or P<0.01),and Logistic analysis showed than the SDS,PC and NC score were the factors influencing the quality of life in patients with CHB(P<0.01).Conclusions The quality of life in patients with CHB is relatively decreased,especially in physiological and psychological fields,which warrants social and clinical concerns.
作者
王新钊
马丽娟
段心科
孙选
王怀海
Wang Xinzhao;Ma Lijuan;Duan Xinke;SUN Xuan3;WANG Huaihai(Department of Gastroenterology,152nd Hospital,Pingdingshan 467000,Henan Province,China)
出处
《实用肝脏病杂志》
CAS
2018年第4期569-572,共4页
Journal of Practical Hepatology
