摘要
目的:探讨来得时联合普通胰岛素强化治疗初发2型糖尿病的可行性。方法:收治初发2型糖尿病患者60例,所有患者在胰岛素治疗基础上,同时应用二甲双胍、阿卡波糖。根据用药治疗方式不同,分为对照组与观察组,各30例。对照组给予诺和灵N联合普通胰岛素治疗,观察组给予来得时联合普通胰岛素强化治疗。结果:两组治疗后FBG、2 h PBG得到有效控制,且优于治疗前(P<0.05);观察组治疗后血糖达标时间、血糖波动值及低血糖发生率优于对照组(P<0.05)。结论:对初发2型糖尿病患者,采用来得时联合普通胰岛素强化治疗,能有效减少胰岛素抵抗与控制血糖水平,促使胰岛β细胞恢复。
Objective:To explore the feasibility of insulin glargine injection combined with normal insulin in the treatment of newly diagnosed type 2 diabetes.Methods:60 patients with type 2 diabetes were selected.On the basis of insulin treatment,metformin and acarbose were used at the same time.According to the different treatment methods,30 cases were divided into the control group and the observation group.The control group were treated with Novolin N combined with ordinary insulin,while the observation group were given insulin glargine injection combined with ordinary insulin for intensive treatment.Results:FBG and 2 h PBG of patients in the two groups were effectively controlled and superior to those before the treatment(P<0.05).The incidence of blood glucose level,blood glucose fluctuation and hypoglycemia in the observation group was lower than that of the control group(P<0.05).Conclusion:Combination of insulin glargine injection and ordinary insulin can effectively reduce insulin resistance and control blood glucose level and promote the recovery of islet beta cells in patients with primary type 2 diabetes.
作者
贾剑森
Jia Jiansen(The Third Department of Internal Medicine,the People's Hospital of Lanshan District of Linyi City in Shandong Province 276000)
出处
《中国社区医师》
2018年第20期30-30,32,共2页
Chinese Community Doctors
关键词
来得时
普通胰岛素
诺和灵N
初发2型糖尿病
Insulin glargine injection
Ordinary insulin
Novolin N
Primary type 2 diabetes mellitus
