摘要
目的:探讨养阴润肺方联合乙酰半胱氨酸治疗老年慢性支气管炎的临床疗效。方法:选择100例老年慢性支气管炎患者作为研究对象,随机分为观察组和对照组,各50例,其中对照组患者给予常规抗炎治疗外加口服乙酰半胱氨酸片治疗,观察组在上述对照组基础上联合养阴润肺方治疗,比较两组患者治疗前后的肺功能指标以及生活质量评分差异,并考察两组患者治疗后的临床效果。结果:两组患者治疗后的FVC、FEV1/预计值、FEV1/FVC%均有显著升高,观察组升高更为显著(P<0.05);与治疗前相比,两组患者治疗后的SGRQ各部分评分均有所降低,观察组患者降低更为显著(P<0.05);治疗后,两组患者免疫球蛋白IgG、IgA与IgM水平上升,且观察组比对照组上升明显(P<0.05);治疗后两组CD_3^+、CD_4^+、CD_8^+、CD_4^+/CD_8^+水平上升,且观察组比对照组明显上升(P<0.05);观察组患者的治疗有效率显著高于对照组(P<0.05)。结论:养阴润肺方联合乙酰半胱氨酸治疗老年慢性支气管炎可以显著降低患者的肺功能指标,改善临床症状,提高生活质量,增强临床疗效。
To explore the clinical effect of Yangyin Runfei prescription combined with acetylcysteine in the treatment of senile chronic bronchitis.Methods:100 elderly patients with chronic bronchitis were selected as the subjects and were randomly divided into the observation group and the control group of 2 groups,each of which 50 cases,the control group was given conventional anti inflammatory treatment plus oral acetylcysteine tablets treatment,and the observation group was combined with the Yangyin Runfei prescription.Compared 2 groups of patients before and after treatment of lung function indicators and quality of life score differences,and investigate the clinical efficacy of 2 groups of patients after treatment.Results:Two groups of patients after the treatment of FVC,FEV1/predicted value,FEV1/FVC%increased significantly,the observation group increased more significantly(P<0.05).Compared with the treatment,the two groups of patients after the treatment of SGRQ scores were reduced,the observation group decreased more significantly(P<0.05);after treatment,the two groups of immunoglobulin IgG,IgA The level of IgM and the observation group increased significantly(P<0.05),and the level of CD 3+,CD 4+,CD 8+and CD 4+/CD 8+increased in the two groups after treatment,and the observation group was significantly higher than the group(P<0.05).The effective rate of the observation group was significantly higher than that of the control group(P<0.05).Conclusion:Yangyin Runfei prescription with acetylcysteine in the treatment of senile chronic bronchitis can significantly reduce the index of lung function,improve the clinical symptoms,improve the quality of life and enhance the clinical effect.
作者
高兵
Gao Bing(Zhengzhou City Center Hospital of Henan Province(Zhengzhou 450000))
出处
《陕西中医》
2018年第8期1044-1047,共4页
Shaanxi Journal of Traditional Chinese Medicine
关键词
支气管炎
慢性/中西医结合疗法
乙酰半胱氨酸/治疗应用
@养阴润肺方
Bronchitis,chronic/integrated
Chinese traditional and western medicine therapy
Acetylcysteine/therapeutic uses
@Yangyin Runfei prescription
