摘要
目的:分析奥拉西坦注射液联合康复训练治疗脑卒中后血管性认知障碍的临床效果。方法:本次选择采用单双数球抽签的方法将在我院接受治疗的48例脑卒中后血管性认知障碍患者分为两组,对照组(康复训练治疗,24例)与实验组(奥拉西坦注射液联合康复训练治疗,24例),分别对两组脑卒中后血管性认知障碍患者的临床治疗效果进行详细分析与比对。结果:实验组的Mo CA评分(27.89±2.17)分明显优于对照组(20.26±1.84)分,具有统计学意义(P<0.05);实验组治疗后的MMSE评分(25.31±3.47)分高于对照组(20.95±2.86)分,具有统计学意义(P<0.05);且实验组的总有效率(95.83%)与对照组(70.83%)相比具有统计学意义(P<0.05);另外,实验组治疗后的ADL评分(47.38±3.89)分优于对照组(40.87±3.64)分,具有统计学意义(P<0.05)。结论:对于脑卒中后血管性认知障碍患者而言,采取奥拉西坦注射液联合康复训练治疗能有效提高患者的认知功能,同时患者的大脑机能与日常生活能力均显著增强与提高,值得临床推广。
Objective:To analyze the clinical effect of oxiracetam injection combined with rehabilitation training in the treatment of vascular cognitive impairment after stroke.Methods:48 patients with vascular cognitive impairment who were treated in our hospital were divided into two groups by single and even ball drawing.The control group(24 cases of rehabilitation training)and the experimental group(24 cases of oxiracetam injection combined with rehabilitation training)were compared with each other in the clinical treatment of vascular cognitive impairment after stroke.Results:The MoCA score of the experimental group was significantly better than that of the control group(27.89±2.17).The MMSE score of the experimental group after treatment was 25.31±3.47,which was significantly higher than that of the control group(20.95±2.86)(P<0.05),and the total effective rate of the experimental group(95.83)was significantly higher than that of the control group(70.83)(P<0.05).The ADL score of the experimental group after treatment was 47.38±3.89,which was significantly higher than that of the control group(40.87±3.64)(P<0.05).Conclusion:For patients with vascular cognitive impairment after stroke,the combination of oxiracetam injection and rehabilitation training can effectively improve the cognitive function of the patients,at the same time,the brain function and daily living ability of the patients are significantly enhanced and improved.It is worth popularizing in clinic.
作者
张会芳
ZHANG Hui-fang(Department of Geriatrics,Xuchang City Hospital;Xuchang Henan 461000,China)
出处
《药品评价》
CAS
2018年第14期51-54,共4页
Drug Evaluation
关键词
奥拉西坦注射液
康复训练
脑卒中
血管性认知障碍
Oxiracetam Injection
Rehabilitation Training
Stroke
Vascular Cognitive Impairment
