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血清甲状腺激素检测在孕期甲状腺疾病筛查中的应用 被引量:5

The Application Value of Serum Thyroid Hormone Levels in the Screening of Thyroid Diseases during Pregnancy
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摘要 目的探究血清甲状腺激素检测在孕期甲状腺疾病筛查中的应用价值。方法选取2016年12月至2017年12月收治的100例孕期甲状腺疾病患者,依据疾病类型分为亚临床甲状腺功能减退的A组(40例),甲状腺功能减退的B组(32例),甲状腺功能亢进的C组(28例);并将同期健康的孕妇设为D组(30例)。分别对4组进行血清甲状腺激素检测。结果 A组游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、总三碘甲状腺原氨酸(TT3)、总甲状腺素(TT4)水平与D组比较,差异无统计学意义(P>0.05),但其促甲状腺素(TSH)水平高于D组(P<0.05);B组FT3、FT4、TT3、TT4水平均低于D组,TSH水平高于D组(P<0.05);C组FT3、FT4、TT3、TT4水平高于D组,TSH水平低于D组(P<0.05)。结论给予孕期甲状腺疾病患者血清甲状腺激素检测具有较高的诊断价值,可作为早期筛选的参考依据。 Objective To explore the value of serum thyroid hormone levels in the screening of thyroid diseases during pregnancy.Methods 100 cases of pregnancy patients with thyroid diseases were selected from December 2016 to December 2017,according to disease classification were divided into A group of subclinical hypothyroidism(40 cases),B group of hypothyroidism(32 cases),and C group of hyperthyroidism(28 cases),and the healthy pregnant women were collected for D group(30 cases).The serum thyroid hormone levels were detected in the 4 groups.Results Free triiodothyronine(FT3),free thyroxine(FT4),total triiodothyronine(TT3),total thyroxine(TT4)levels showed no significant difference between the A group and D group(P>0.05);thyrotropin(TSH)level was significantly different between the A group and D group(P<0.05).The levels of FT3,FT4,TT3 and TT4 in group B were lower than those in D group,but the level of TSH was higher than that of D group(P<0.05).The levels of FT3,FT4,TT3 and TT4 in group C were higher than those in D group,but the level of TSH was lower than that of D group(P<0.05).Conclusion The serum thyroid hormone level for patients with thyroid disease during pregnancy is of high diagnostic value,which can be used as a reference for early screening.
作者 肖爱娜 张艳丽 Xiao Aina;Zhang Yanli(Basic College of Ningxia Medical University,Yinchuan Ningxia 750004;Ningxia people's Hospital,Yinchuan Ningxia 750004,China)
出处 《医疗装备》 2018年第13期8-10,共3页 Medical Equipment
关键词 甲状腺激素 孕期 甲状腺疾病 筛选 Thyroid hormone Pregnancy Thyroid disease Screening
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