摘要
目的探讨低剂量阿司匹林在夫精人工授精中的应用效果。方法选择2017年5月~2017年12月进行夫精人工授精患者200例,根据患者是否采用阿司匹林分为对照组和观察组,每组100例。对照组IUI周期均未使用阿司匹林,观察组月经干净后服低剂量阿司匹林至IUI手术当日。记录并统计两组HCG注射当天子宫内膜厚度、子宫内膜类型及子宫动脉血流阻力指数(RI)水平;记录并统计A型内膜占比及临床妊娠率,比较两组临床效果及对临床妊娠率的影响。结果观察组子宫内膜厚度大于对照组(P<0.05);观察组RI水平低于对照组(P<0.05);观察组A型内膜占比、临床妊娠率均高于对照组(P<0.05)。结论对于无使用阿司匹林禁忌证患者,行夫精人工授精时常规添加低剂量的阿司匹林可有效提高临床妊娠率。
Objective To investigate the effect of low-dose aspirin on artificial insemination in husbandry.Methods A total of 200 patients who had undergone artificial sperm fertilization in May 2017 to December 2017 were selected.Patients were divided into a control group and an observation group according to whether they used aspirin or not.Each group contained 100 patients.In the control group,aspirin was not used during the IUI cycle.The observation group was clean after menstruation and took low-dose aspirin until the day of IUI operation.Record and count the endometrial thickness,endometrial type and uterine arterial resistance index(RI)on the two groups of HCG injection day;record and count the proportion of type A endometrial and clinical pregnancy rate;compare the clinical effects of two groups and the effect of clinical pregnancy rate.Results The endometrial thickness of the observation group was greater than that of the control group(P<0.05).The level of RI in the observation group was lower than that of the control group(P<0.05).The ratio of type A intima and clinical pregnancy rate in the observation group was higher than that in the control group(P<0.05).Conclusion For patients without aspirin contraindication,routine addition of low-dose aspirin during artificial insemination can effectively increase the clinical pregnancy rate.
作者
帅妹
黄云
吴润香
岳林林
Shuai Mei;Huang Yun;Wu Runxiang;Yue Linlin(Department of Reproductive,Ganzhou Maternal and Child Health Care Hospital,Ganzhou,Jiangxi,341000,China)
出处
《当代医学》
2018年第22期100-102,共3页
Contemporary Medicine
基金
江西省卫生计生委科技计划(20177268)
关键词
阿司匹林
夫精人工授精
应用效果
临床妊娠率
化学发光免疫分析仪
Aspirin
Fujing artificial insemination
Application effect
Clinical pregnancy rate
Chemiluminescence immunoassay
