摘要
目的:探究氯吡格雷联合阿司匹林治疗社区老年冠心病的临床疗效。方法:收治老年冠心病患者90例,随机分为两组。两组患者给予他汀类降脂药物、抗凝等冠心病常规药物治疗。对照组在此基础上采用阿司匹林治疗,试验组在对照组基础上给予氯吡格雷药物治疗。比较两组临床疗效、血小板聚集率(PAG)及凝血相关指标的变化、不良反应。结果:治疗后试验组总有效率显著高于对照组,试验组治疗后PAG、活化部分凝血酶时间(APTT)优于对照组,试验组不良反应发生率显著低于对照组,差异有统计学意义(P<0.05)。结论:氯吡格雷联合阿司匹林治疗老年冠心病的临床疗效理想。
Objective:To explore the clinical effect of clopidogrel combined with aspirin in the treatment of elderly patients with coronary heart disease in community.Methods:90 cases of elderly patients with coronary heart disease were divided into two groups randomly.The clinical effect,platelet aggregation rate(PAG),coagulation related indexes and adverse reactions were compared between the two groups.Results:After treatment,the total effective rate of the experiment group was significantly higher than that of the control group.After treatment,PAG and APTT in the experiment group were better than those in the control group.The incidence of adverse reactions in the experiment group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:Clopidogrel combined with aspirin was effective in the treatment of senile coronary heart disease.
作者
李韫
Li Yun(The Sixth People's Hospital of Chengdu City(Sichuan)610000)
出处
《中国社区医师》
2018年第26期59-60,共2页
Chinese Community Doctors
关键词
氯吡格雷
阿司匹林
老年冠心病
Clopidogrel
Aspirin
Senile coronary heart disease
