摘要
目的:分析维持性腹膜透析患者的疾病控制效果与影响因素的临床研究。方法:收集进行透析治疗的患者170例,其中采用血液透析患者81例为对照组,采用持续性腹膜透析患者89例为观察组,分析比较两组患者治疗前后血肌酐(SCr)、血尿素(BUN)及治疗后的疾病缓解率和缓解时间,并对影响治疗效果的危险因素和多因素进行Logistic回归分析。结果:①观察组患者在治疗后的血肌酐(SCr)、血尿素(BUN)依次为(371.83±87.59)μmol/L、(10.69±3.06)mmol/L,均低于对照组患者(P均<0.05)。②治疗后观察组患者的疾病缓解率为100%、缓解时间(4.32±0.58)d,明显优于对照组的的89.89%和(9.26±2.73)d(P均<0.05);③Logistic回归分析显示,体重较重者、尿素清除指数低及合并心脑血管疾病者疾病控制的主要影响险因素(P均<0.05)。结论:持续性腹膜透析对于患者疾病的控制有良好的临床效果,患者能够在较短时间内缓解病情,多因素Logistic回归分析中,患者的体重、尿素清除指数、合并心血管疾病是影响腹膜透析患者治疗效果的主要因素。
Objective:To analyze the clinical study of disease control effect and influencing factors in patients with maintenanceive peritoneal dialysis.Methods:170 patients with dialysis were retrospectively analyzed.Among them,81 patients with hemodialysis were as the control group,89 patients with persistent peritoneal dialysis were as the observation group.The levels of serum creatinine(SCr),blood urea(BUN)and the remission rate and remission time of the patients were analyzed before and after treatment.And the risk influencing factors affecting the effect were taken for multivariate logistic regression analysis.Results:①The levels of serum creatinine(SCr)and blood urea(BUN)in the observation group were(371.83±87.59umol/L)and(10.69±3.06mmol/L),significantly lower than those in the control group(P<0.05).②The remission rate was 100%and the remission time was(4.32±0.58)d in the observation group,were significantly better than that of the control group of(89.89%)and(9.26±2.73)d(P<0.05).③Logistic regression analysis showed that the weight of severe weight,low urea clearance index and the control of cardiovascular and cerebrovascular disease were the main impact of risk factors(P<0.05).Conclusion:Persistent peritoneal dialysis has a good clinical effect on the control of patients'disease.The patients can relieve the condition in a short time,and multivariate logistic regression analysis shows the patient's body weight,urea clearance index,combined with cardiovascular disease are the main factors affecting the treatment of patients with peritoneal dialysis.
作者
李涛
冯晓晨
纪玲玲
肖坤
Li Tao;Feng Xiaochen;Ji Lingling(Department of Nephrology,Zhongshan Hospital Affiliated to Dalian University,Dalian 116001)
出处
《陕西医学杂志》
CAS
2018年第9期1127-1129,1133,共4页
Shaanxi Medical Journal
基金
辽宁省科技攻关计划项目(2014235324)
关键词
肾疾病/治疗
腹膜透析
预后
Kindney diseases/therapy
Peritoneal dialysis
Prognosis
