摘要
目的:研究并探讨血液透析用于慢性肾衰竭合并急性心力衰竭临床治疗的临床价值。方法:选择慢性肾衰竭合并急性心力衰竭患者100例,采取计算机随机数字分组法将患者随机分为对照组、观察组,每组患者50例。对照组患者采取常规内科治疗,观察组患者在常规内科治疗基础上施加血液透析治疗,比较两组患者的临床疗效、心功能指标、肾功能指标。结果:观察组临床治疗总有效率96%,对照组总有效率82%,两组比较,有统计学差异(P<0.05);心功能指标方面,治疗后,两组患者的左心射血分数、NT-proBNP均明显优于治疗前(P<0.05),而在治疗后两组比较,观察组的左心射血分数明显高于对照组(P<0.05),其NT-proBNP表达水平明显低于对照组(P<0.05);肾功能指标方面,治疗后,观察组患者的血肌酐、尿素氮均明显低于治疗前(P<0.05),且其低于对照组治疗后(P<0.05)。结论:在慢性肾衰竭合并急性心力衰竭患者的临床治疗中,对患者实施血液透析治疗,可有效提高患者的临床治疗效果,可对患者的心功能和肾功能起到更加显著的改善作用,有利于改善患者预后。
Objective:To study the clinical value of hemodialysis in the treatment of chronic renal failure with acute heart failure.Methods:100 patients with chronic renal failure complicated with acute heart failure were randomly divided into control group(n=50)and control group(n=50).The patients in the control group were treated with routine medical treatment,the patients in the observation group were treated with hemodialysis on the basis of routine medical treatment,and the clinical efficacy,cardiac function index and renal function index were compared between the two groups.Results:The total effective rate of clinical treatment in the observation group was 96 and that in the control group was 82.There was statistical difference between the two groups(P<0.05).The left ventricular ejection fraction(NT-proBNP)in the two groups was significantly higher than that in the control group(P<0.05),while the left ventricular ejection fraction in the observation group was significantly higher than that in the control group(P<0.05),and the expression of NT-proBNP in the observation group was significantly lower than that in the control group(P<0.05),and in the renal function index,after treatment,the expression of NT-proBNP in the observation group was significantly lower than that in the control group(P<0.05).The levels of serum creatinine and urea nitrogen in the observation group were significantly lower than those before treatment(P<0.05)and lower than those in the control group(P<0.05).Conclusion:In the clinical treatment of patients with chronic renal failure and acute heart failure,the treatment of hemodialysis can effectively improve the effect of the patients'clinical treatment,and can improve the cardiac function and renal function of the patients more significantly,which is beneficial to the improvement of the patients.
作者
李丹
谷学梅
Li Dan;Gu Xuemei(Department of Rheumatism,Nephropathy Hospital,Shaoguan First People's Hospital,Shaoguan 512000)
出处
《陕西医学杂志》
CAS
2018年第9期1161-1163,共3页
Shaanxi Medical Journal
