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肝纤维四项诊断晚期血吸虫病肝纤维化的价值 被引量:6

The Value of Four Indicators of Liver Fibrosis in the Diagnosis of Advanced Schistosomiasis Liver Fibrosis
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摘要 目的分析肝纤维四项在晚期血吸虫病肝纤维化诊断中的应用价值。方法以2014年1月—2017年1月在本院接受治疗的100例晚期血吸虫病肝纤维化患者(观察组)和100例健康体检者(对照组)作为研究对象,都接受肝纤维四项检测,利用B超检查评估观察组100例患者肝纤维化程度,分为肝纤维化Ⅱ级和肝纤维化Ⅲ级。比较对照组和观察组、肝纤维化Ⅱ级和肝纤维化Ⅲ级的肝纤维四项指标。结果观察组PC-Ⅲ(101.56±52.16)ng/ml、IV-C(90.54±23.31)ng/ml、LN(127.52±20.62)ng/ml、HA(371.01±28.21)ng/ml,高于对照组(P <0.05);肝纤维化Ⅲ级PC-Ⅲ(123.10±11.14)ng/ml、 IV-C(98.63±12.10)ng/ml、 LN(132.54±15.63)ng/ml、 HA(389.54±27.10)ng/ml,高于肝纤维化Ⅱ级(P <0.05)。结论检测肝纤维四项指标可以评估晚期血吸虫病患者肝纤维化程度,结果较为准确。 Objective To analyze the application value of four liver fibers in the diagnosis of advanced schistosomiasis liver fibrosis.Methods One hundred patients with advanced schistosomiasis liver fibrosis(observation group)and 100 healthy subjects(control group)who were treated in our hospital from January 2014 to January 2017 were treated with liver fibrosis.The index test,using B-ultrasound to assess the observation group of 100 patients with liver fibrosis,divided into liver fibrosis gradeⅡand liver fibrosis gradeⅢ.The four indicators of liver fibrosis were compared between control group and observation group,liver fibrosis gradeⅡand liver fibrosis gradeⅢ.Results In the observation group,the PC-Ⅲ(101.56±52.16)ng/ml,IV-C(90.54±23.31)ng/ml,LN(127.52±20.62)ng/ml,and HA(371.01±28.21)ng/ml were higher than the control group(P<0.05);In liver fibrosis gradeⅢPC-Ⅲ(123.10±11.14)ng/ml,IV-C(98.63±12.10)ng/ml,LN(132.54±15.63)ng/ml,HA(389.54±27.10)ng/ml,higher than liver fibrosis gradeⅡ(P<0.05).Conclusion The detection of four indicators of liver fibrosis can be used to assess the degree of hepatic fibrosis in patients with advanced schistosomiasis,the results are more accurate.
作者 王英 WANG Ying(Department of Clinical Laboratory,Third People's Hospital of Suzhou,Suzhou Jiangsu 215300,China)
出处 《中国继续医学教育》 2018年第27期41-43,共3页 China Continuing Medical Education
关键词 晚期血吸虫病 肝纤维化 肝纤维四项指标 诊断 PC-Ⅲ IV-C LN HA advanced schistosomiasis liver fibrosis four indicators of liver fibrosis diagnosis PC-III IV-C LN HA
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