摘要
目的探讨PWI和DWI在毛细胞型星形细胞瘤(PA)与高级别星形细胞瘤(HGA)鉴别诊断中的应用价值。方法回顾性分析经手术病理证实的22例PA与41例HGA患者的常规MR、PWI及DWI资料。计算PA和HGA的相对脑血容量值(rCBV)及相对表观弥散系数值(rADC)。采用独立样本t检验及ROC曲线对数据进行分析。结果 PA的rCBV值(1.82±1.05)明显低于HGA(5.07±1.49),PA的rADC值(1.98±0.60)明显高于HGA(0.99±0.29),差别均有统计学意义(P<0.01)。当以rCBV值>3.02或rADC值≤1.24作为诊断HGA的阈值时,rCBV与rADC值具有较高的诊断准确率。2条ROC曲线下的面积AUCrCBV和AUCrADC分别为0.97及0.92,二者差别无统计学意义(P>0.05)。结论PWI和DWI对PA和HGA的鉴别诊断具有重要价值。
Objective To evaluate the usefulness of perfusion-weighted imaging and diffusion-weighted imaging in the differentiation of pilocytic astrocytomas(PA)from high-grade astrocytomas(HGA). Methods Conventional MR imaging,PWI,and DWI were performed on 22 patients with PA and 41 patients with HGA. All lesions were confirmed by histopathology and the images were retrospectively reviewed. Relative cerebral blood volumes values were calculated from perfusion-weighted imaging and relative apparent diffusion coefficient values were calculated form diffusion-weighted imaging in each tumor. Independent t test and receiver operating characteristic(ROC)curve were used for statistical analysis. Results The rCBV values in PA were significantly lower than that in HGA[(1.82±1.05)vs(5.07±1.49),P<0.01). The rADC values in PA were significantly higher than that in HGA[(1.98±0.60)vs(0.99±0.29),P<0.01]. With the ROC curve analysis,if the rCBV 3.02 or rADC 1.24 was taken as a threshold to predict HGA,the high accuracy of rCBV and rADC could be reached. Conclusion Perfusion-weighted imaging and diffusion-weighted imaging are helpful in discriminating pilocytic astrocytomas from high-grade astrocytoma.
作者
李玉萍
陈群林
曹代荣
佘德君
杨谢锋
郑颖彦
LI Yuping;CHEN Qunlin;CAO Dairong;SHE Dejun;YANG Xiefeng;ZHENG Yingyan(Department of Radiology,The First Affiliated Hospital of Fujian Medical University,Fuzhou 350005,China)
出处
《福建医科大学学报》
2018年第3期200-203,共4页
Journal of Fujian Medical University
关键词
磁共振波谱学
毛细胞
听觉
星形细胞瘤
磁共振成像
magnetic resonance spectroscopy
hair cells,auditory
astrocytoma
magnetic resonance imaging
