摘要
目的探讨齐拉西酮与奥氮平治疗老年精神分裂症的临床意义。方法随机将我院2016年8月—2017年8月收治的70例老年精神分裂症患者分为两组,每组35例。对照组给予奥氮平治疗,观察组给予齐拉西酮治疗。比较两组临床疗效。结果 (1)治疗后,对照组血糖指标、血脂指标及BMI等与观察组比较差异有统计学意义(P<0.05);(2)治疗后,两组PANSS评分、总有效率差异无统计学意义(P>0.05)。结论齐拉西酮与奥氮平均可有效治疗老年精神分裂症,但齐拉西酮基本不会影响血糖及血脂等指标水平,避免了不良反应情况的出现,提高了患者的生活质量。
Objective To explore the clinical significance of ziprasidone and olanzapine in the treatment of senile schizophrenia.Methods 70 elderly schizophrenic patients in our hospital from August 2016 to August 2017 were randomly divided into two groups,35 cases in each group.The control group was given olanzapine,and the observation group was given ziprasidone.The clinical effects of two groups were compared.Results(1)After treatment,the blood glucose index,blood lipid index,BMI in control compared with the observation group,the difference was significant(P<0.05).(2)The total effective difference between the two groups was not significant(P>0.05).Conclusion The effect of ziprasidone and ortzone can effectively treat senile schizophrenia,but ziprasidone can not affect the level of Blood glucose and blood lipid,it can avoids the occurrence of adverse reactions and improves the quality of life of the patients.
作者
洪军
HONG Jun(Psychiatry Department,Mudanjiang Neuropsychiatric Hospital,Mudanjiang Heilongjiang 157014,China)
出处
《中国继续医学教育》
2018年第23期97-99,共3页
China Continuing Medical Education
关键词
齐拉西酮
奥氮平
老年精神分裂症
血糖
血脂
临床疗效
ziprasidone
olanzapine
senile schizophrenia
blood glucose
blood lipid
clinical efficacy
