摘要
胆红素代谢异常是引发新生儿黄疸的重要原因之一,严重时会导致核黄疸的发生,对新生儿的神经系统造成不可逆的损伤,对新生儿体内胆红素浓度进行实时检测对预防核黄疸的发生有着重要意义。本文设计了基于双探测器的实时黄疸检测系统,根据朗伯-比尔定律和皮肤组织中物质对光的吸收特性,从理论上分析出黄疸检测系统测得的电压值与胆红素浓度之间的关系。通过实验与数据分析,得到胆红素浓度与电压值之间的线性关系式。进行验证性试验,线性方程的测量误差均值为6μmol/L,符合黄疸检测精度要求。
Abnormal metabolism of bilirubin is one of the important causes of neonatal jaundice.In severe cases,it causes kernicterus and irreversible damage to the neonatal nervous system.Therefore,real-time detection of bilirubin concentration in neonates is important for preventing the occurrence of nuclear jaundice.In this paper,a real-time detection system based on double detectors was designed.According to Beer-Lambert law and absorption properties of light in the skin tissue,it was theoretically analyzed that the relationship between the voltage value and the bilirubin concentration was measured by the detection system.Through experiments and data analysis,a linear relationship between bilirubin concentration and voltage value was obtained.Verification tests were carried out and the mean value of the measurement error of the linear equation was 6umol/L,which meet the requirements for the detection accuracy of the jaundice.
作者
武姝君
李英
周哲
贾克
付威威
WU Shujun;LI Ying;ZHOU Zhe;JIA Ke;FU Weiwei(School of Optoelectronic Engineering,Changchun University of Science and Technology,Changchun 130022;Suzhou Institute of Biomedical Engineering and Technology Chinese Academy of Sciences,Suzhou 215163)
出处
《长春理工大学学报（自然科学版）》
2018年第5期25-27,32,共4页
Journal of Changchun University of Science and Technology(Natural Science Edition)
