摘要
目的探讨水解蛋白多维营养粉在食管癌患者术后的临床应用。方法采用对照研究,共纳入60例食管癌患者,分为实验组和对照组,各30例。实验组在常规营养治疗基础上,口服或管饲水解蛋白多维营养粉(术和~);对照组给予常规营养治疗,共7天。观察比较两组患者术后初次排气时间、第3天和第7天相关营养指标、腹泻发生率等,以P<0.05表示差异有统计学意义。结果经过营养治疗后,实验组患者术后的初次排气时间显著提前[实验组:(56.01±8.88)小时,对照组:(62.52±7.63)小时;P=0.00],腹泻发生率显著低于对照组,差异均具有统计学意义,恶心、呕吐等一般胃肠道耐受性症状的发生率与对照组相当。两组患者的相关营养指标均有不同程度的改善趋势。实验组患者的前白蛋白水平显著高于对照组患者,差异有统计学意义,但血清总蛋白、白蛋白、转铁蛋白水平无统计学差异。结论水解蛋白多维营养粉(术和~)能有效改善食管癌术后患者体内的负氮平衡,促进胃肠功能恢复,具有良好的胃肠道耐受性,对于食管癌术后患者的临床治疗具有指导意义。
Objective To investigate the clinical application value of protein hydrolysate multi-nutrient powder in esophageal cancer postoperative patients.Methods Sixty esophageal cancer postoperative patients were divided into the experimental group and the control group,30 cases in each group.The experimental group received routine nutritional therapy,while protein hydrolysate multi-nutrient powder was administered orally or tube-fed,and the control group received routine nutritional therapy for a total of seven days.The time of initial exhaust,the relevant nutritional indicators and the incidence of abdominal diarrhea etc on the third day and the seventh day were observed and compared respectively,the differences between the two groups were significant differences(P<0.05).Results After the nutritional therapy,the time of initial exhaust of the patients in the experimental group was significantly earlier[in the experimental group:(56.01±8.88)h,in the control group:(62.52±7.63)h;P=0.00)],the incidence of abdominal diarrhea was significantly lower than that of the control group,the differences were statistically significant.The incidence of nausea and vomiting was with no difference of the control group.The two groups of patients related to nutritional indicators had different degrees of improvement trend.The levels of prealbumin were significantly higher in the experimental group than that in the control group,the differences were statistically significant,but the serum total protein and albumin and transferrin between the two groups were with no statistical differences.Conclusions protein hydrolysate multi-nutrient powder can effectively improve the negative nitrogen balance,promote gastrointestinal function recovery,with good gastrointestinal tolerance.It is of guiding significance to the clinical treatment of postoperative patients with esophageal cancer.
作者
卢开进
侯莉莉
LU Kai-jin;HOU Li-li(Department of the Thoracic Surgery,the People’s Hospital of Taizhou,Taizhou 225300,Jiangsu,China;Department of Clinical Nutrition,the People’s Hospital of Taizhou,Taizhou 225300,Jiangsu,China)
出处
《肿瘤代谢与营养电子杂志》
2018年第2期170-174,共5页
Electronic Journal of Metabolism and Nutrition of Cancer
关键词
营养治疗
前白蛋白
白蛋白
排气时间
食管癌
Nutrition therapy
Prealbumin
Albumin
Exhaust time
Esophageal cancer
