摘要
目的探讨急性脑梗死患者再灌注治疗(静脉溶栓、血管内治疗、桥接治疗)后静脉充盈早现现象与颅内出血转化的关系。方法纳入符合再灌注治疗的急性脑梗死患者98例,在血管达到TICI 2b/3级再通后,依据数字减影血管造影(DSA)过程中静脉充盈早现征象的有无分为静脉充盈早现组(30例)和无静脉充盈早现组(68例),比较两组颅内出血转化的发生率。结果静脉充盈早现组有16例发生了颅内出血转化,无静脉早现组12例发生出血转化,两组比较(53. 3%vs 17. 6%),差异有统计学意义(P <0. 05)。静脉早现现象对颅内出血转化预测的敏感度为57%、特异度80%。结论急性脑梗死再灌注治疗后出现静脉充盈早现征象预测并发脑出血的风险较大。
Objective To investigate the relationship between early venous filling and intracranial hemorrhage after reperfusion therapy in patients with acute cerebral infarction.Methods 98 patients with acute cerebral infarction were enrolled in this study.After reperfusion of TICI 2b/3.According to the presence or absence of early venous filling signs during digital subtraction angiography,the patients were divided into two groups:the early venous filling group(30 cases)and the non-early venous filling group(68 cases).The incidence of intracranial hemorrhage transformation was compared between the two groups.Results There were 16 cases of intracranial hemorrhage transformation in the early venous filling group,12 cases in the non-early venous filling group,and the difference between the two groups(53.3%vs 17.6%)was statistically significant(P<0.05).The sensitivity of prediction of intracranial hemorrhage is 57%and specificity is 80%.Conclusion The early venous filling after reperfusion in acute cerebral infarction can predict the risk of cerebral hemorrhage.
作者
温宏峰
王瑞彤
李继来
王培福
WEN Hongfeng;WANG Ruitong;LI Jilai(Department of Neurology,Aerospace Center Hospital,Beijing 100049,China)
出处
《中风与神经疾病杂志》
CAS
2018年第10期889-892,共4页
Journal of Apoplexy and Nervous Diseases
基金
首都临床特色应用研究与成果推广(No.Z17110700100000)
北京市科技重大专项(No.Z171100001017137)
关键词
急性脑梗死
再灌注治疗
静脉充盈早现
出血转化
Acute cerebral infarction
Reperfusion therapy
Early venous filling
Hemorrhagic transformation
