摘要
目的研究反流性食管炎(reflux esophagitis,RE)与胃食管阀瓣(gastroesophageal flap valve,GEFV)分级的相关性,分析RE发生的危险因素。方法选取2015年1月至2016年12月本院接诊的302例RE患者为研究对象,根据胃镜影像对患者GEFV进行分级。分析GEFV分级与RE分级的相关性、RE患者GEFV分级与治疗方案的关系,并分析RE发生的危险因素。结果随着GEFV分级的增加,RE分级也随之增加,两者呈正相关(r=0.126,P <0.05);随着GEFV分级的增加,接受手术治疗的患者例数亦增加,两者之间呈正相关(r=0.455,P <0.001);预后良好组患者和预后不良组患者的年龄、性别、RE家族史、高血压病史、饮酒史、高脂血症病史、GEFV分级比较差异均具有显著性(P_均<0.05),两组患者住院天数比较无显著差异(P> 0.05);Logistic回归分析显示:年龄、性别、RE家族史、高血压病史、糖尿病病史、饮酒、高脂血症病史、GEFV分级为影响RE发生的危险因素。结论 GEFV分级判断RE患者病情严重程度具有一定的应用价值,接受手术治疗的RE患者随着GEFV分级的增加而增加。
Objective The correlation between reflux esophagitis(RE)and gastroesophageal(GEFV)classification was studied to analyze the risk factors of RE occurrence.Method 302 RE patients who admitted treatment in our hospital from January 2015 to December 2016 were selected as research objects,and GEFV was graded according to the gastroscopic images.The correlation between the GEFV grading and RE grading,the relationship between GEFV grading of RE patients and the treatment regimen,and the risk factors of RE occurrence were analyzed.Result With the increase of GEFV classification,RE classification also increased,and there was positive correlation between them(r=0.126,P<0.05).With the increase of GEFV classification,the number of patients accepting surgical treatment also increased,and there was positive correlation between them(r=0.455,P<0.001).There were significant differences in age,sex,RE family history,history of hypertension,history of drinking,history of hyperlipemia,GEFV classification between good prognosis group and poor prognosis group(Pall<0.05),there was no significant difference in hospitalization days between the two groups(P>0.05).Logistic regression analysis showed that age,gender,family history of RE,history of hypertension,history of diabetes,alcohol consumption,history of hyperlipemia,and GEFV classification were risk factors for the occurrence of RE.Conclusion The evaluation of severity of RE patients by GEFV classification has certain application value.With the increase of GEFV classification,the number of RE patients receiving surgical treatment increases accordingly.
作者
柯冀
伍冀湘
李建业
于磊
KE Ji;WU Ji-xiang;LI Jian-ye;YU Lei(Department of Thoracic Surgery,Beijing Tongren Hospital,Capital Medical University, Beijing 100730,China;Department of General Surgery,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China)
出处
《中国医学前沿杂志（电子版）》
2018年第10期126-130,共5页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
关键词
反流性食管炎
胃食管阀瓣
相关性
危险因素
Reflux esophagitis
Gastroesophageal flap valve
Correlation
Risk factor
