摘要
目的探讨孟鲁司特钠联合吸入型糖皮质激素治疗小儿哮喘的临床效果。方法选取我院2017年1月～2018年1月收治的80例哮喘患儿作为研究对象,按照随机抽样法分为对照组(40例)与观察组(40例),对照组给予布地奈德进行治疗,观察组采用孟鲁司特钠联合布地奈德进行治疗。比较两组的临床疗效、肺功能指标(FEV1、PEF)、病症素现消失时间住院时间、不良反应总发生率。结果观察组治疗后的总有效率高于对照组,差异有统计学意义(P<0.05);观察组治疗后的肺功能指标高于对照组,差异有统计学意义(P<0.05);观察组的病症素现消失时间住院时间短于对照组,差异均有统计学意义(P<0.05)。结论孟鲁司特钠联合吸入型糖皮质激素治疗小儿哮喘的临床效果十分明显,改善患儿的肺功能,缩短住院时间,值得临床推广应用。
Objective To explore the clinical effect of Montelukast Sodium combined with inhaled corticosteroids in the treatment of children with asthma.Methods Eighty children with asthma admitted to our hospital from January 2017 to January 2018 were selected as the study subjects and randomly divided into control group(40 cases)and observation group(40 cases)according to random sampling,the control group was treated with Budesonide,while the observation group was treated with Montelukast Sodium combined with Budesonide.The clinical efficacy,pulmonary function indexes(FEV1,PEF),the time of disappearance of symptoms length of stay and total incidence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group after treatment was higher than that of the control group,the difference was statistically significant(P<0.05).The lung function indexs of the observation group after treatment were higher than those of the control group,the difference was statistically significant(P<0.05).The Length of stay and the time of disappearance of symptoms in the observation group were shorter than those of the control group,the differences were statistically significant(P<0.05).Conclusion The clinical effect of Montelukast sodium combined with inhaled glucocorticoid in the treatment of children with asthma is very obvious,and it can improve the pulmonary function of children,shorten hospital stay,worthy of clinical promotion and application.
作者
顾婷婷
GU Ting-ting(Department of Paediatrics,Maternal and Infant Hospital of Liaohe Oilfield General Hospital,Liaoning Province,Panjin 124010,China)
出处
《中国当代医药》
2018年第29期76-78,共3页
China Modern Medicine
