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左西孟旦治疗急性心力衰竭患者的效果及其对血清脑钠肽的作用 被引量:3

Effect of levosimendan in the treatment of patients with acute heart failure and its effect on serum brain natriuretic peptide
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摘要 目的:探讨左西孟旦治疗急性心力衰竭患者的临床效果以及对血清脑钠肽水平的影响。方法:收治急性心力衰竭患者94例,分为两组,每组各47例。对照组给予盐酸多巴酚胺注射液治疗,观察组在对照组基础上给予左西孟旦注射液治疗,比较两组治疗总有效率、不良反应发生率以及心功能指标。结果:观察组治疗总有效率高于对照组,不良反应发生率低于对照组,差异有统计学意义(P<0.05)。两组治疗后每搏输出量、脑钠肽、左室射血分数比较,差异有统计学意义(P<0.05)。结论:左西孟旦治疗急性心力衰竭患者可降低血清脑钠肽水平。 Objective:To investigate the clinical effect of levosimendan in the treatment of patients with acute heart failure and its effect on serum brain natriuretic peptide.Methods:94 cases of patients with acute heart failure were divided into two groups.The control group was treated with dopamine hydrochloride injection,while the observation group was treated with levosimendan injection on the basis of the control group,the total effective rate,adverse reaction rate and cardiac function index were compared between the two groups.Results:The total effective rate of the observation group was higher than that of the control group,and the incidence of adverse reactions was lower than that of the control group,and the difference was statistically significant(P<0.05).There were significant differences in output per beat,brain natriuretic peptide and left ventricular ejection fraction between the two groups after treatment(P<0.05).Conclusion:Levosimendan could reduce the level of serum brain natriuretic peptide in patients with acute heart failure.
作者 胡兴丽 Hu Xingli(Department of Cardiovascular,Guizhou Aerospace Hospital(Zunyi)563000)
出处 《中国社区医师》 2018年第32期71-72,共2页 Chinese Community Doctors
关键词 左西孟旦 急性心力衰竭 脑钠肽 临床效果 Levosimendan Acute heart failure Brain natriuretic peptide Clinical effect
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