摘要
糖尿病心肌病(diabetic cardiomyopathy,DCM)可导致糖尿病患者心力衰竭甚至死亡,是糖尿病的一种严重的并发症。早期表现为能量代谢、心肌脂肪变性、微循环灌注异常等,逐步发展为心肌细胞重塑、心功能异常和心肌纤维化等。DCM起病隐匿,致病分子机制尚未完全阐明,诊断标准不明确。目前可通过一些影像学检查间接检测心肌细胞可能存在的病理改变,做出诊断,及时干预,并监测病情发展,逆转或延缓病情,改善预后。本文就DCM病程中不同阶段的影像检测方法进行相关综述。
Diabetic cardiomyopathy(DCM)can lead to heart failure or even death in diabetic patients,which is a serious complication of diabetes mellitus.The early manifestations of DCM include abnormal energy metabolism,myocardial steatosis,abnormal microcirculation perfusion,etc.And might gradually develop into myocardial cell remodeling,cardiac dysfunction,and myocardial fibrosis.The pathogenesis of DCM has not been fully elucidated.The diagnostic criteria are unclear.At present,we can indirectly detect the possible pathological changes of cardiomyocytes with the help of imaging examinations,therefore to make a diagnosis,intervene in time,monitor the development of the disease,reverse or delay the condition,and improve the prognosis.In this paper,the imaging detection methods in different stages of DCM are reviewed.
作者
迟庆杰
王天乐
祁荣兴
CHI Qing-jie;WANG Tian-le;QI Rong-xing(Department of Medical Imaging,the Second Affiliated Hospital of Nantong University,Nantong 226001,Jiangsu,China)
出处
《中国临床医学》
2018年第5期815-820,共6页
Chinese Journal of Clinical Medicine
基金
南通市关键技术研究-民生项目(MS22015061)
南通市民生科技创新和示范推广项目(MS12016065)
南通市关键技术研究-农业与社发-民生事业及临床诊疗项目(GJZ17015)~~
关键词
糖尿病
影像诊断
能量代谢
心肌脂肪变性
微循环灌注
心功能
心肌纤维化
diabetes mellitus
imaging diagnosis
energy metabolism
myocardial fatty degeneration
microcirculatory perfusion
cardiac function
myocardial fibrosis
