摘要
壳聚糖作为一种天然高分子有机物,具有良好的生物相容性、可降解性和抗菌性,在抗菌方面已有一定的应用,但其抗菌性能易受自身因素和外界条件的影响,因此如何巩固和加强壳聚糖的抗菌性能并进行应用成为了研究的热点。将壳聚糖与无机物纳米材料复合,有机和无机组分协同互补,能显著提高材料的抗菌性能,复合材料还具有优异的机械强度和生物相容性,可广泛应用于水处理、食品、纺织、化妆品和医学等领域,引起了科研人员的密切关注。本文总结了壳聚糖的抗菌机理和影响抗菌性能的因素,详细介绍了壳聚糖与金属、金属氧化物、层状硅酸盐和碳材料等无机物复合后的纳米材料在抗菌方面的应用,同时对其在抗菌领域的发展前景进行了展望。
As a natural organic polymer,chitosan shows excellent biocompatibility,biodegradability and antimicrobial properties and it has already been used as an antimicrobial agent.Nevertheless,the antimicrobial properties of chitosan are easily influenced by its own factors and external conditions,which hinders its broad application.Therefore,strengthen the antimicrobial activity and promote the application of chitosan have become the focus research.When chitosan is incorporated into inorganic nanomaterials to form composite materials,a synergistical complementary effect of organic and inorganic components can be acquired,which will dramatically improve the antimicrobial activity of the materials.Thanks to the favorable mechanical strength and biocompatibility,chitosan/inorganic nanocomposites have been extensively applied in the field of water treatment,food,textile,cosmetics,medicine and aroused great interests of researchers.In this article,the mechanisms and influencing factors of antimicrobial properties of chitosan are summarized.The preparation and application of nanocomposites of chitosan and inorganic materials like metal,metal oxide,layered silicate,carbon materials in antimicrobial field are introduced in detail,and their prospective for development in the antimicrobial field is proposed as well.
作者
李旭飞
车阳丽
吕艳
刘芳
王永强
赵朝成
LI Xufei;CHE Yangli;LYU Yan;LIU Fang;WANG Yongqiang;ZHAO Chaocheng(College of Chemical Engineering,China University of Petroleum,Qingdao 266580)
出处
《材料导报》
EI
CAS
CSCD
北大核心
2018年第21期3823-3830,共8页
Materials Reports
基金
山东省自然科学基金(ZR201702140013)
中国石油大学(华东)拔尖人才资助项目(RC17040003)
中国石油大学(华东)研究生金点子项目(JDZ1705016)
