摘要
目的研究坤泰胶囊结合快步走运动对更年期女性性激素及血脂代谢的影响。方法门诊120例更年期患者随机分成坤泰胶囊治疗组和坤泰胶囊运动组,每组55例。比较2组治疗前、治疗4周和12周时血清性激素[雌二醇(E2)、卵泡刺激素(FSH)、黄体生成素(LH)]和血脂水平[三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)],以及2组12周治疗前后的血脂正常率。结果 2组均能提高E2水平,坤泰胶囊运动组提高效果更明显(P <0. 05); 2组均能降低LH水平,坤泰胶囊运动组降低效果更明显(P <0. 05);2组均能降低FSH水平,且2组降低效果差异无统计学意义(P> 0. 05)。2组均能降低TG水平,坤泰胶囊运动组降低效果更明显(P <0. 05); 2组均能提高HDL-L水平,坤泰胶囊运动组提高效果更明显(P <0. 05),2组对TC无显著影响,坤泰胶囊运动组可以降低低密度脂蛋白(LDL-C)水平,而坤泰胶囊组降低效果差异无统计学意义(P> 0. 05)。结论坤泰胶囊结合快步走运动比单纯口服坤泰胶囊更有效地改善更年期女性血脂及性激素水平。
Objective To observe the effects of Kuntai capsule combined with brisk walking on the sex hormones and blood lipid metabolism in perimenopausal women.Methods One hundred and twenty perimenopausal women were randomly divided into Kuntai capsule group(n=55)and Kuntai capsule+exercise group(n=55).The perimenopausal women in Kuntai capsule group were treated by simple Kuntai capsule,however,the perimenopausal women in Kuntai capsule+exercise group were treated by Kuntai capsule combined with brisk walking,with a treatment course of 12 weeks for both groups.The seum levels of sex hormones and blood lipid before treatment and at 4 weeks,12 week after treatment were observed and compared between the two groups.Moreover the normal rates of blood lipids before and after 12-week treatment were observed and compared between the two groups.Results After treatment the serum levels of estradiol were increased in both groups,however,the improvement effects in Kuntai capsule+exercise group were more significant than those in Kuntai capsule group(P<0.05).The serum levels of luteotropic hormone were decreased in both groups,and the improvement effects in Kuntai capsule+exercise group were more significant than those in Kuntai capsule group(P<0.05).Moreover the serum levels of follicule-stimulating hormone were decreased in both groups,however,there were no significant differences between the two groups(P>0.05).The serum levels od TG were decreased in both groups,the decrease effects in Kuntai capsule+exercise group were more significant than those in Kuntai capsule group(P<0.05).In addition the serum levels of HDL-C were increased in both groups,and the improvement effects in Kuntai capsule+exercise group were more significant than those in Kuntai capsule group(P<0.05).Besides both group had no obvious effects on TC levels,but Kuntai capsule+exercise group could decrease LDL-C levels significantly,but Kuntai capsule group had no significant effects on LDL-C levels(P>0.05).Conclusion Kuntai capsule combined with brisk walking can more effectively improve the serum levels of sex hormones and blood lipid in perimenopausal women,as compared with simple Kuntai capsule.
作者
邱巍峰
李海燕
宁雪朋
何洁
QIU Weifeng;LI Haiyan;NING Xuepeng(Department of Gynecology,The Third Hospital of Shijiazhuang City,Hebei,Shijiazhuang 050011,China)
出处
《河北医药》
CAS
2018年第22期3436-3438,3442,共4页
Hebei Medical Journal
基金
石家庄市科技局计划项目(编号:141462873)
关键词
更年期综合征
坤泰胶囊
快步走
性激素
血脂
climacteric syndrome
Kuntai capsule
brisk walking
sex hormone
blood lipid
