摘要
目的研究血尿酸与老年女性患者脑白质疏松的相关性。方法以123例老年女性为研究对象,根据脑白质疏松程度分为2组(无-轻度组,中-重度组),分析两组患者中一般统计学资料及实验室指标,分析尿酸与脑白质疏松之间的关系。结果通过对无-轻度组和中-重度组之间数据的资料比较,发现中-重度组患者尿酸、叶酸水平较高(P <0. 05),而白蛋白水平较低(P <0. 05)。经Logistic分析发现,尿酸是脑白质疏松的独立危险因素,并且尿酸水平与脑白质疏松严重程度呈正相关(r=0. 574,P <0. 01)。结论老年女性人群中,尿酸水平越高,脑白质疏松程度越严重。
Objective To study the correlation between serum uric acid and leukoaraiosis in elderly women.Methods A total of 123 subjects were collected from the aged women.According to the degree of leukoaraiosis,all of the women were divided into 2 groups(no-mild group,moderate-severe group),the general statistical data and laboratory indexes were analyzed in the two groups,and the relationship between uric acid and leukoaraiosis was analyzed.Results By comparing data between the two groups,it was found that the levels of uric acid and folic acid were higher in the middle-severe group(P<0.05),but the level of albumin was lower(P<0.05).Logistic analysis showed that uric acid was an independent risk factor for leukoaraiosis,and uric acid level was positively correlated with leukoaraiosis(r=0.574,P<0.01).Conclusion In the elderly female population,when the uric acid level higher,the leukoaraiosis more serious.
作者
卢丹丹
李红闪
万莉
祖赛
齐丹丹
王佩
LU Dandan;LI Hongshan;WAN Li(Department of 3rd Neurology,Baoding No.1 Central hospital,Baoding 071000,China)
出处
《中风与神经疾病杂志》
CAS
2018年第11期1000-1002,共3页
Journal of Apoplexy and Nervous Diseases
基金
河北省保定市科技局科技支撑计划(No.17zf068)
关键词
尿酸
脑白质疏松
老年女性
Uric acid
Leukoaraiosis
Elderly women
