摘要
目的探索阿奇霉素序贯治疗儿童支原体肺炎的疗效和安全性。方法选取2017年8月23日—2018年8月23日我院支原体肺炎100例患儿(实施奇偶数分组模式),对照组的50例患儿采用红霉素治疗,观察组的50例患儿采用阿奇霉素序贯治疗,随后对比两组总有效率、不良反应总发生率、C反应蛋白(CRP)、降钙素原(PCT)、血沉、咳嗽消失时间、肺部啰音消失时间、发热消失时间、住院时间。结果观察组CRP(7.15±1.33)mg/L、PCT(0.33±0.08)μg/L、血沉(11.25±2.62)mm/h、总有效率(94.00%)、不良反应总发生率(2.00%)、肺部啰音消失时间(5.26±1.96)d、咳嗽消失时间(3.15±1.33)d、发热消失时间(3.69±1.75)d、住院时间(10.75±2.65)d,均优于对照组(P <0.05)。结论对支原体肺炎小儿实施阿奇霉素序贯治疗效果显著。
Objective To explore the efficacy and safety of azithromycin sequential in the treatment of children with mycoplasmal pneumonia.Methods 100 children with mycoplasmal pneumonia in our hospital from August 23,2017 to August 23,2018 were enrolled in the study.They were divided into two groups according to the odd and even methosd.The 50 patients in the control group were treated with erythromycin,the 50 patients in the observation group were treated with azithromycin sequential,then the total effective rate,the incidence of adverse reactions,C-reactive protein(CRP),procalcitonin(PCT),erythrocyte sedimentation,cough disappearance time,disappearance time of lung voice,fever disappearance time,hospitalization time were compared between the two groups.Results In the observation group,the level of CRP was(7.15±1.33)mg/l,the level of PCT was(0.33±0.08)μg/L,the level of erythrocyte sedimentation was(11.25±2.62)mm/h,total effective rate was 94.00%,the incidence of adverse reactions was 2.00%,disappearance time of lung voice was(5.26±1.96)d,cough disappearance time was(3.15±1.33)d,fever disappearance time was(3.69±1.75)d,hospitalization time was(10.75±2.65)d,which were all better than those of the control group(P<0.05).Conclusion The effect of azithromycin sequential on children with mycoplasmal pneumonia is obvious.
作者
陈巧芹
CHEN Qiaoqin(Department of Pediatrics,Wuxi Second People's Hospital, Wuxi Jiangsu 214000,China)
出处
《中国继续医学教育》
2018年第34期130-132,共3页
China Continuing Medical Education
关键词
阿奇霉素
序贯
支原体肺炎
安全性
咳嗽
红霉素
炎症反应
azithromycin
sequential
mycoplasmal pneumonia
safety
cough
erythromycin
inflammatory response
