摘要
目的探讨苯巴比妥钠预防原发性肾病综合征患者肾穿刺活检术后并发症的效果。方法选取医院2016年8月至2018年2月收治的原发性肾病综合征并接受肾穿刺活检术的住院患者240例,按住院顺序单双号排序分为观察组与对照组,各120例。肾穿刺活检术前30 min,对照组患者肌肉注射注射用水1 m L,观察组患者肌肉注射苯巴比妥钠1 m L。结果治疗后,观察组患者焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、视觉模拟评分(VAS)、收缩压、舒张压、并发症总发生率均明显低于对照组(P <0. 01);观察组患者住院时间明显短于对照组,住院费用明显低于对照组(P <0. 01)。结论苯巴比妥钠可有效改善原发性肾病综合征肾穿刺活检术患者的焦虑抑郁情绪、疼痛程度及血压变化程度,降低并发症发生率,缩短住院时间,减少住院费用。
Objective To investigate the effect of phenobarbital in the prevention of complications of renal biopsy in patients with primary nephrotic syndrome( PNS). Methods Totally 240 patients with PNS undergoing renal biopsy admitted to our hospital from August 2016 to February 2018 were selected and divided into the observation group( odd numbers) and the control group( even numbers)according to the order of hospitalization,120 cases in each group. 30 min before renal biopsy,the control group was intramuscularly injected with 1 m L of water for injection,while the observation group was intramuscularly injected with 1 m L of phenobarbital sodium.Results After treatment,the SAS score,SDS score,VAS score,systolic blood pressure,diastolic blood pressure and the total incidence rate of complications in the observation group were significantly lower than those in the control group( P < 0. 05). The hospitalization time in the observation group was significantly shorter than that in the control group,and the hospitalization cost was significantly lower than that in the control group( P < 0. 01). Conclusion Phenobarbital sodium can effectively improve the anxiety and depression,pain and blood pressure changes in patients with PNS undergoing renal biopsy,it also can reduce the incidence of complications,shorten hospitalization time and reduce hospitalization cost.
作者
王婧
赵宝青
戴鹏
赵讯
王学敏
王向托
Wang Jing;Zhao Baoqing;Dai Peng;Zhao Xun;Wang Xuemin;Wang Xiangtuo(Department of Renal Medicige,Hengshui People's Hospital,Hengshui,Hebei,China 053000)
出处
《中国药业》
CAS
2018年第24期43-45,共3页
China Pharmaceuticals
基金
河北省衡水市科技计划项目[2016014093Z]
关键词
苯巴比妥钠
原发性肾病综合征
肾穿刺活检术
并发症
预防
焦虑
抑郁
血压
住院时间
phenobarbital sodium
primary nephrotic syndrome
kidney biopsy
complications
prevention
anxiety
depression
blood pressure
hospitalizationtime
