摘要
目的探讨糖尿病合并动脉硬化患者的心血管疾病情况。方法选取2015年1月～2016年1月医院收治的186例糖尿病患者,按照是否合并动脉硬化分为合并组和未合并组,对两组患者的血压、甘油三脂、总胆固醇水平进行检测,比较两组患者心血管疾病的发病情况。通过分析ROC曲线计算动脉硬化对于心血管疾病的敏感度、特异度和界值。结果合并组患者的收缩压、舒张压、甘油三脂、总胆固醇水平分别为(140.24±22.45)mm Hg、(94.24±13.35)mm Hg、(4.23±1.42)mmol/L、(5.67±1.85)mmol/L,未合并组患者的收缩压、舒张压、甘油三脂、总胆固醇水平分别为(115.24±23.45)mm Hg、(74.24±11.25)mm Hg、(2.21±1.72)mmol/L、(4.26±0.65)mmol/L,数据比较差异有统计学意义(P <0.05)。合并组患者心血管疾病分布情况为冠心病48例(48.97%)、心肌梗塞27例(27.55%),未合并组患者心血管疾病分布情况为冠心病18例(20.45%)、心肌梗塞8例(9.09%),数据比较差异有统计学意义(P <0.05)。颈动脉、下肢动脉硬化以及两者合并硬化对心血管疾病检测的敏感度和特异度分别为87.5%和50%、68.41%和87.5%、62.5%和85.42%,数据比较差异有统计学意义(P <0.05)。结论糖尿病合并动脉硬化患者发生心血管疾病的概率较高,颈动脉硬化和颈动脉硬化合并下肢动脉硬化对心血管检测的敏感度和特异度较高,可作为一项临床预测指标。
Objective To explore the cardiovascular disease situation in diabetes patients with arteriosclerosis.Methods186patients with diabetes admitted to the hospital from January2015to January2016were selected and divided into combined group and uncombined group according to whether combined arteriosclerosis.Blood pressure,triglyceride and total cholesterol levels were measured in the two groups,and the incidence of cardiovascular disease was compared between the two groups.The sensitivity,specificity and boundary value of arteriosclerosis for cardiovascular disease were calculated by analyzing the ROC curve.Results The systolic blood pressure,diastolic blood pressure,triglyceride,and total cholesterol levels in the combined group were(140.24±22.45)mm Hg,(94.24±13.35)mm Hg,(4.23±1.42)mmol/L,and(5.67±1.85)mmol/L.The systolic blood pressure,diastolic blood pressure,triglyceride,and total cholesterol levels in the uncombined group were(115.24±23.45)mm Hg,(74.24±11.25)mm Hg,(2.21±1.72)mmol/L and(4.26±0.65)mmol/L,the data difference was statistically significant(P<0.05).The distribution of cardiovascular disease in the combined group was48cases(48.97%)with coronary heart disease and27cases(27.55%)with myocardial infarction.The distribution of cardiovascular disease in the uncombined group was18cases(20.45%)with coronary heart disease and8cases with myocardial infarction(9.09%),the difference was statistically significant(P<0.05).The sensitivity and specificity of carotid artery,lower extremity arteriosclerosis,and combined sclerotherapy for cardiovascular disease respectively were87.5%and50%,68.41%and87.5%,62.5%and85.42%,the difference was statistically significant(P<0.05).Conclusion Diabetic patients with arteriosclerosis have a higher probability of cardiovascular disease.Carotid atherosclerosis and carotid atherosclerosis combined with lower extremity arteriosclerosis have higher sensitivity and specificity for cardiovascular detection,it can be used as a clinical predictor.
作者
樊金宇
孙宇琦
刘婵娟
杜超
FAN Jinyu;SUN Yuqi;LIU Chanjuan;DU Chao(Laboratory Department,Second Affiliated Hospital of Mudanjiang Medical College,Mudanjiang 157000,China)
出处
《中国医药科学》
2018年第21期162-164,181,共4页
China Medicine And Pharmacy
关键词
动脉硬化
糖尿病
心血管病
ROC曲线
Arteriosclerosis
Diabetes
Cardiovascular disease
ROC curve
