摘要
目的:探讨精神分裂症患者出院后药物治疗依从性及相关影响因素。方法:对175例出院后的精神分裂症患者进行6个月的随访调查,通过电话、入户或门诊随访完成自编《精神分裂症患者药物治疗依从性调查问卷》,分析患者出院后药物治疗依从性及影响依从性的相关危险因素。结果:精神分裂症患者出院后药物治疗依从率仅为61. 1%(107/175例);影响患者出院后药物治疗依从性的危险因素包括缺乏疾病相关知识(OR=2. 319,95%CI:1. 56～3. 07)、药物不良反应(OR=6. 209,95%CI:4. 768～7. 650)、药物种类(OR=1. 931,95%CI:1. 257～2. 605)、对医师的信任较差(OR=2. 855,95%CI:1. 908～3. 801)、门诊不定期复诊(OR=3. 300,95%CI:2. 181～4. 419)及缺乏家庭支持(OR=4. 319,95%CI:2. 935～5. 703)等(P <0. 05或P <0. 001)。结论:精神分裂症患者出院后的药物治疗依从性较差,与缺乏疾病相关知识、药物不良反应、不定期复诊、缺乏家庭支持等影响因素有关。
Objective:To explore the drug treatment compliance and related influencing factors of schizophrenia patients after leaving hospital.Method:Using following-up study design,175schizophrenia patients who left hospitals were investigated.The treatment compliance questionaire was completed by home interview,telephone or outpatiment interview.Drug treatment compliance of schizophrenia patients after leaving hospital and related influencing factors were analyzed.Results:The rate of good drug treatment compliance was61.1%(107/175).The influential factors for drug treatment compliance in schizophrenia patients after leaving hospital included lack of knowledge regarding the disorder(OR=2.319,95%CI:1.56-3.07),adverse drug reaction(OR=6.209,95%CI:4.768-7.650),drug types(OR=1.931,95%CI:1.257-2.605),poor trust in doctors(OR=2.855,95%CI:1.908-3.801),unscheduled visits to the outpatient clinic(OR=3.300,95%CI:2.181-4.419)and lack of family support(OR=4.319,95%CI:2.935-5.703)(all P<0.05or P<0.001).Conclusion:There is a poor drug treatment compliance in schizophrenia patients after leaving hospital.The influencing factors include lack of knowledge related to the disorder,drug adverse reaction,unscheduled visits to the outpatient clinic and lack of family support.
作者
符彬
徐孟松
FU Bin;XU Meng-song(Psychiatry Department of the Seventh People's Hospital of Cixi City,Cixi315336,China)
出处
《临床精神医学杂志》
2018年第6期412-414,共3页
Journal of Clinical Psychiatry
关键词
精神分裂症
药物治疗
依从性
影响因素
schizophrenia
antipsychotic drugs
compliance
influencing factors
