摘要
目的探讨降钙素原(PCT)、C反应蛋白(CRP)联合检测在慢性阻塞性肺疾病急性加重期(AECOPD)中的临床意义。方法该院肺病科收治的AECOPD患者63例,其中细菌感染组41例、非细菌感染组22例;同期体检健康者35例纳入对照组。检测所有受试对象血清PCT和CRP水平,分析其对AECOPD细菌感染的诊断效能。结果细菌感染组PCT和CRP水平明显高于非细菌感染组和对照组(P<0.05);PCT、CRP及二者联合检测对AECOPD细菌感染的诊断特异度分别为90.1%、78.3%、94.6%,灵敏度分别为81.3%、90.4%、91.7%,联合检测的诊断特异度和灵敏度均高于PCT、CRP单独检测。结论 PCT、CRP联合检测对AECOPD细菌感染具有较高的诊断价值。
Objective To explore the clinical significance of combined detection of procalcitonin(PCT)and C reaction protein(CRP)in acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods 63 cases of AECOPD were enrolled as case group,including 41 cases in bacterial infection group and 22 cases in non?bacterial infection group.35 healthy subjects were enrolled as control group.Serum levels of PCT and CRP were measured and the diagnostic performance for AECOPD was analyzed.Results PCT and CRP levels were significantly higher in the bacterial infection group than the non-bacterial infection group and the control group(P<0.05).The diagnostic specificity of PCT,CRP and PCT+CRP were 90.1%,78.3%and 94.6%,respectively.And the sensitivity was 81.3%,90.4%and 91.7%,respectively.The specificity and sensitivity of PCT combined with CRP were higher than PCT and CRP alone.Conclusion Combined detection of PCT and CRP could be with high diagnostic performance in AECOPD.
出处
《现代医药卫生》
2018年第24期3787-3788,3791,共3页
Journal of Modern Medicine & Health
关键词
慢性阻塞性肺疾病急性加重期
降钙素原
C反应蛋白
感染
Acuteexacerbation of chronicobstructive pulmonary disease
Procalcitonin
C-reactionprotein
Infection
