摘要
目的研究参附注射液对化疗后晚期乳腺癌患者免疫功能及生活质量的作用。方法观察180例化疗后晚期乳腺癌患者进行不同药物治疗的疗效,将我院2015年1月～2018年1月收治的180例化疗后晚期乳腺癌患者随机均分两组,以常规治疗为对照,分析参附注射液治疗价值,评估两组患者治疗有效率、CD4、CD8、CD4/CD8、NK细胞水平、生活质量评分,分别采用χ~2检验、t检验。结果治疗后,观察组治疗有效率88.89%,远较对照组的58.89%高,且观察组CD4、CD8、CD4/CD8、NK细胞水平、生活质量评分均远高于对照组,两组差异有统计学意义(P <0.05)。结论参附注射液是一种科学的治疗方案,对改善化疗后晚期乳腺癌患者免疫功能,提高生活质量具有重要意义。
Objective To study the effect of Shenfu injection on immune function and quality of life after chemotherapy in patients with advanced breast cancer.Methods Curative effects of different drug treatments for 180 patients with advanced breast cancer after chemotherapy were observed.180 patients with advanced breast cancer who were treated with chemotherapy in our hospital from January 2015 to January 2018 were randomly divided into two groups.Patients receiving routine treatment were set as the control group to analyze curative effect of Shenfu injection.The effective rate of treatment,CD4,CD8,CD4/CD8,NK cell level and quality of life score of patients in two groups were evaluated.Chi-square test and t-test were used respectively.Results After treatment,effective rate of treatment in the observation group was 88.89%,significantly higher than that in the control group 58.89%.CD4,CD8,CD4/CD8,NK cell level and quality of life score of the observation group were significantly higher than those in the control group.Difference between two groups were statistically significant(P<0.05).Conclusion Shenfu injection is a scientific treatment plan,which is of great significance in improving the immune function and improving the quality of life after chemotherapy of patients with advanced breast cancer.
作者
王济国
WANG Jiguo(Department of Oncology,Baoan District Hospital of Traditional Chinese Medicine,Shenzhen 518133,China)
出处
《中国医药科学》
2018年第22期18-20,175,共4页
China Medicine And Pharmacy
基金
广东省深圳市宝安区科技创新局医疗卫生科研项目(2016CX027)
关键词
化疗
晚期乳腺癌
参附注射液
免疫功能
生活质量
Chemotherapy
Advanced breast cancer
Shenfu injection
Immune function
Quality of life
