摘要
目的探讨上消化道术后手术部位感染常见的细菌种类及其耐药性。方法回顾性分析2011年1月—2016年2月我院普通外科的113例上消化道术后手术部位感染病人的细菌培养及药敏资料。结果 113例病人共送检标本115份,培养出细菌135株,其中革兰阴性杆菌109株(80.7%),革兰阳性球菌20株(14.8%),真菌6株(4.4%);常见的感染菌依次为铜绿假单胞菌38株(28.2%),大肠埃希菌30株(22.2%),肺炎克雷伯杆菌17株(12.6%),鲍曼不动杆菌10株(7.4%),阴沟肠杆菌10株(7.4%),均为肠道内正常居留菌。上述常见革兰阴性杆菌对一二代头孢类抗生素的耐药率多在50%左右,大肠埃希菌、肺炎克雷伯杆菌及阴沟肠杆菌对亚胺培南、美罗培南的耐药率均较低。结论上消化道术后病人手术部位感染的病原菌以革兰阴性杆菌为主,为控制感染及耐药菌播散,需合理应用抗生素。
Objective To investigate the bacteria causing surgical site infection after upper gastrointestinal surgery and their drug resistance.Methods A retrospective analysis was performed for bacterial culture and drug sensitivity data of 113 patients with surgical site infection after upper gastrointestinal surgery who were treated in the Department of General Surgery in our hospital from January 2011 to February 2016.Results A total of115specimens were collected from these patients.A total of 135 strains were cultured,among which there were 109 strains(80.7%)of Gram-negative bacilli,20 strains(14.8%)of Gram-positive cocci,and 6 strains(4.4%)of fungi.Common bacteria included Pseudomonas aeruginosa(38strains,28.2%),Escherichia coli(30strains,22.2%),Klebsiella pneumoniae(17strains,12.6%),Acinetobacter baumannii(10strains,7.4%),and Enterobacter cloacae(10strains,7.4%),and all of them were normal intestinal inhabitants.The Gram-negative bacilli had a drug resistance rate of about 50% to the first-and second-generation cephalosporins,and Escherichia coli,Klebsiella pneumoniae,and Enterobacter cloacae had a low drug resistance rate to imipenem and meropenem.Conclusion Gram-negative bacilli are the main pathogenic bacteria of surgical site infection in patients after upper gastrointestinal surgery.Antibiotics should be rationally used to control infection and the spread of drug-resistant bacteria.
作者
牛冬光
李晨
方洪春
权琳
刘鹏
丁连安
NIU Dongguang;LI Chen;FANG Hongchun;QUAN Lin;LIU Peng;DING Lianan(Gastrointestinal Surgery Department,The Affiliated Hospital of Qingdao University,Qingdao 266100,China)
出处
《青岛大学学报（医学版）》
CAS
2018年第6期721-723,727,共4页
Journal of Qingdao University(Medical Sciences)
关键词
外科伤口感染
上胃肠道
消化系统外科手术
细菌
抗药性
微生物
surgical wound infection
upper gastrointestinal tract
digestive system surgical procedures
bacteria
drug resistance,microbial
