摘要
目的评价小儿伤食方、益气养阴方预防小儿反复呼吸道感染的临床疗效和安全性。方法 2015年7月至2016年7月厦门市中医院门诊收治小儿反复呼吸道感染患儿(胃肠积热证或气阴两虚证)90例,随机分为观察组和对照组各45例。观察组根据患儿体质分别给予小儿伤食方、益气养阴方适时治疗,持续干预1年,并随访1年,对照组不做干预。观察治疗前后两组呼吸道感染病种、次数、病程及疗效。结果治疗后两组在发病次数、病程及病种方面均有所改善,观察组明显优于对照组,差异有统计学意义(P<0.05)。随访12个月后,观察组在上呼吸道感染及气管炎次数方面减少明显优于对照组,差异有统计学意义(P<0.05)。治疗后两组肺炎发病次数均降低,但两组比较差异无统计学意义(P>0.05)。观察组疗效优于对照组,差异有统计学意义(P<0.05)。两组均未报道不良事件及不良反应的发生。结论小儿伤食方、益气养阴方在小儿反复呼吸道感染适时使用,可明显减少呼吸道感染发生。
Objective To evaluate the clinical efficacy and safety of Shang Shi Fang and Yi Qi Yang Yin Fang in preventing recurrent respiratory tract infection(RRTI)in children.Methods From July2015to July2016,90children with RRTI were treated in the Outpatient Department of Xiamen Hospital of Traditional Chinese Medicine(gastrointestinal heating or Qi-Yin-deficiency syndrome),who were randomly divided into observation group(n=45)and control group(n=45).According to the physical constitution of the children,the observation group was given timely treatment with Shang Shi Fang and Yi Qi Yang Yin Fang,with continuous intervention for1year and follow-up for1year,while the control group was not intervened.The types,frequency,course and curative effect of respiratory tract infection were observed before and after treatment.Results After treatment,both groups got improved in the frequency,course and types of disease,and the observation group was significantly superior to the control group,with statistically significant differences(P<0.05).After12months of follow-up,the observation group was significantly better than the control group in the reduction of frequency of upper respiratory tract infection and tracheitis(P<0.05).The incidence of pneumonia decreased in both groups after treatment,but the difference was not statistically significant(P>0.05).The effect of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).No adverse events or adverse reactions were reported in both groups.Conclusion It can reduce the incidence of recurrent respiratory tract infection in children to use Shang Shi Fang and Yi Qi Yang Yin Fang at a proper time.
作者
高树彬
欧阳晓燕
GAO Shubin;OUYANG Xiaoyan(Xiamen Hospital of Traditional Chinese Medicine,Xiamen 361009,China)
出处
《中国中西医结合儿科学》
2018年第6期466-469,共4页
Chinese Pediatrics of Integrated Traditional and Western Medicine
基金
厦门市2015科技惠民计划(3502Z20154061)
关键词
反复呼吸道感染
体质
治未病
儿童
Recurrent respiratory tract infections
Constitution
Preventive treatment of disease
Child
