摘要
目的探讨补阳还五汤联合天麻钩藤饮对脑梗死的临床疗效。方法收集入院的80例脑梗死患者随机分为2组,传统组患者给予传统西医治疗,中药联合组患者则加用补阳还五汤联合天麻钩藤饮,比较2组患者神经状态、中医证候、疾病相关参数与总体效果。结果中药联合组治疗后神经功能缺损评分(NIHSS)显著性低于传统组,日常生活活动能力量表(BI)显著高于传统组(P <0. 05);治疗4周后,上下肢活动不遂、口舌歪斜、言语謇涩或不语、感觉评分、同型半胱胺酸(Hcy)、C反应蛋白(CRP)、D-二聚体、纤维蛋白原(FIB)、肿瘤坏死因子(TNF)与神经元烯醇化酶(NSE)水平均显著低于传统组(P <0. 05);总有效率明显高于传统组(P <0. 05)。结论补阳还五汤联合天麻钩藤饮对脑梗死的临床疗效显著。
Objective To investigate the clinical effect of Buyang Huanwu Decoction and Tianma Gouteng Decoction on treating cerebral infarction.Methods A total of 80 patients with cerebral infarction were randomly divided into two groups.The traditional group was treated with traditional western medicine,and the combined group was given Buyang Huanwu Decoction and Tianma Gouteng Decoction on the basis of traditional group.The neurological status,TCM syndromes,disease-related parameters and overall effects of the two groups were compared.Results The National Institutes of Health Stroke Scale(NIHSS)score in combined group was significantly lower,and Barthel Index(BI)was higher than that in the traditional group(P<0.05).After 4-week treatment,four extremities activity,tongue slant or speechless,sensory score,homocysteine(Hcy),C-reactive protein(CRP),D-dimer,fibrinogen(FIB),tumor necrosis factor(TNF)and neuronal enolase(NSE)levels were all lower than that in the traditional group(P<0.05).And total efficacy of two groups were higher than that in the traditional group(P<0.05).Conclusion The combination of Buyang Huanwu Decoction and Tianma Gouteng Decoction has significant clinical efficacy for cerebral infarction.
作者
李俊
周东升
LI Jun;ZHOU Dongsheng(Department of Traditional Chinese Medicine,Pingli County Hospital,Ankang,Shaanxi,725500;Department of Traditional Chinese Medicine,Langao County Hospital,Ankang,Shaanxi,725400)
出处
《实用临床医药杂志》
CAS
2019年第1期40-43,共4页
Journal of Clinical Medicine in Practice
基金
陕西省卫生厅科研项目基金(2016M486951)
关键词
补阳还五汤
天麻钩藤饮
脑梗死
中医证候
Buyang Huanwu Decoction
Tianma Gouteng Decoction
cerebral infarction
TCM syndrome
