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阿奇霉素与甲泼尼龙治疗肺炎支原体肺炎分析 被引量:2

Analysis of Azithromycin and Methylprednisolone in the Treatment of Mycoplasma Pneumoniae Pneumonia
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摘要 目的分析肺炎支原体肺炎采用阿奇霉素联合甲泼尼龙治疗的临床疗效。方法选取2017年1月—2018年8月于我院收治的肺炎支原体肺炎患儿85例作为研究对象,将其随机分为两组。对照组单独采用阿奇霉素治疗,观察组采用阿奇霉素联合甲泼尼龙治疗,对比两组症状改善时间、临床疗效。结果观察组退热时间为(5.75±1.02)d,短于对照组的(7.86±1.52)d;观察组咳嗽消失时间为(5.91±1.22)d,短于对照组的(8.89±2.63)d;观察组肺部啰音消失时间为(6.62±1.52)d,短于对照组的(9.26±2.15)d;观察组胸片阴影消失时间为(7.05±1.08)d,短于对照组的(12.89±2.11)d,组间各数据比较,差异均具有统计学意义(t=9.315 9、6.098 2、4.068 4、7.838 0,P <0.05);与对照组(78.57%)对比,观察组患者的治疗总有效率(95.35%)更高,组间比较,差异具有统计学意义(χ~2=5.308 4,P <0.05)。结论肺炎支原体肺炎采用阿奇霉素联合甲泼尼龙治疗的临床疗效显著,能更快缓解患儿的临床症状,提高治疗有效率。 Objective To analyze the clinical efficacy of azithromycin combined with methylprednisolone in the treatment of mycoplasma pneumoniae pneumonia. Methods 85 children with mycoplasma pneumoniae pneumonia admitted to our hospital from January 2017 to August 2018 were randomly divided into two groups. The control group was treated with azithromycin alone. The observation group was treated with Azithromycin combined with methylprednisolone. The improvement time and clinical effect of the two groups were compared. Results The antipyretic time of the observation group was(5.75±1.02) days, which was shorter than that of the control group(7.86±1.52) days. The disappearance time of cough in the observation group was(5.91±1.22) days, which was shorter than that in the control group(8.89±2.63) days. The disappearance time of lung rales in the observation group was(6.62±1.52) days, shorter than that in the control group(9.26±2.15) days, and the disappearance time of chest shadow in the observation group was(7.05±1.08) days, shorter than that in the control group(12.89±2.11) days. There were significant differences in the data between the two groups(t=9.315 9, 6.098 2, 4.068 4, 7.838 0, P < 0.05). Compared with the control group(78.57%), the total effective rate of treatment in the observation group(95.35%) was higher, and the difference between the two groups was statistically significant(χ~2=5.308 4, P < 0.05). Conclusion The clinical effect of azithromycin combined with methylprednisolone in the treatment of mycoplasma pneumoniae pneumonia is remarkable. It can relieve the clinical symptoms of children more quickly and improve the treatment efficiency.
作者 金羽 JIN Yu(Department of Pediatrics,Xiangcheng People's Hospital,Suzhou Jiangsu 215131,China)
出处 《中国继续医学教育》 2018年第36期83-85,共3页 China Continuing Medical Education
关键词 肺炎支原体肺炎 阿奇霉素 甲泼尼龙 联合治疗 有效性 临床特征 mycoplasma pneumoniae pneumonia azithromycin methylprednisolone combination therapy effectiveness clinical characteristics
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