摘要
目的研究脑卒中后癫痫患者采用丙戊酸钠与左乙拉西坦的联合治疗效果。方法择取108例脑卒中后癫痫患者(收治时间在2016年8月—2017年8月),采用随机数字表法将患者平均分为观察组(予以丙戊酸钠联合左乙拉西坦治疗)和对照组(予以丙戊酸钠治疗),每组54例。对比两组患者的具体治疗效果。结果观察组和对照组治疗总有效率对比(96.29%vs77.78%),差异有统计学意义(χ~2=8.206 7,P=0.004 1<0.05)。观察组患者的运动能力评分[(86.56±5.98)分vs (60.26±4.99)分],差异有统计学意义(t=24.814 1,P=0.000 0 <0.05)。生活能力评分[(79.64±8.65)分vs (58.64±4.59)分]优于对照组,差异有统计学意义(t=15.758 9,P=0.000 0 <0.05)。观察组和对照组治疗不良反应发生率对比(3.70%vs 24.07%),差异有统计学意义(χ~2=9.3677,P=0.002 2 <0.05)。结论对脑卒中后癫痫患者采用丙戊酸钠与左乙拉西坦的联合治疗,效果显著,可以提升患者的生活能力以及运动能力,护理满意度更高,值得临床使用和推广。
Objective To study the combined effect of sodium valproate and levetiracetam in patients with epilepsy after stroke. Methods108 patients with epilepsy after stroke(from August 2016 to August 2017) were randomly divided into observation group and the con-trol group by random number table of(sodium valproate combined with levetiracetam treatment) and(treated with sodium valproate),54 patients in each group. Compare the specific treatment effects of the two groups of patients. Results The total effective rate of ob-servation group and control group was compared(96.29% vs 77.78%), The difference was statistically significant(χ~2=8.206 7, P=0.004 1<0.05). The exercise ability scores of the observation group(86.56±5.98) points vs(60.26±4.99) points, the difference was statistically significant(t=24.814 1, P=0.000 0<0.05). The ability of life score(79.64±8.65) points vs(58.64±4.59) points was better than the control group, and the difference was statistically significant(t=15.758 9, P=0.000 0<0.05). The incidence of adverse reactions in the observation group and the control group were compared(3.70% vs 24.07%), and the difference was statistically significant(χ~2=9.367 7,P=0.002 2<0.05). Conclusion The combination of sodium valproate and levetiracetam is effective in patients with post-stroke epilep-sy. It can improve the patient’s ability to live and exercise, and the nursing satisfaction is higher, which is worthy of clinical use and promotion.
作者
刘晏辰
LIU Yan-chen(Department of Anesthesiology,Changhai Hospital,the First Affiliated Hospital of Shanghai Naval Medical University,Shanghai,200082 China)
出处
《世界复合医学》
2018年第4期69-71,共3页
World Journal of Complex Medicine
关键词
丙戊酸钠
左乙拉西坦
脑卒中
癫痫
生活能力
不良反应
Sodium valproate
Levetiracetam
Stroke
Epilepsy
Living ability
Adverse reactions
