摘要
该研究制备的多孔金电极敏感加强型AlN基薄膜体声波传感器谐振频率为1. 214 58 GHz,利用Hg^(2+)核酸适配体修饰金电极,形成Hg^(2+)生物敏感层。通过T-Hg^(2+)-T双碱基对结构特异性俘获目标物Hg^(2+)离子,对Hg^(2+)在50～1 000 n Mol/L浓度范围内器件频率大小进行了实时监测。实验发现,在100～1 000 n Mol/L浓度范围内,器件频率漂移量和Hg^(2+)浓度之间呈线性关系,检测灵敏度约为677. 07 Hz/nMol/L,器件灵敏度高,选择性好。
The resonant frequency of the prepared AlN based thin film bulk acoustic resonator(FBAR) with a porous gold electrode was 1.21458 GHz,which was modified by the Hg^2+ nucleic acid ligands to form a sensitive layer.Based on the T-Hg^2+-T double base pair specific reactio n,the resonant frequency shifts of various Hg^2+ concentrations in the range of 50~1000 nMol/L were measured.Experiments show that the resonance frequency of the sensor decreases proportionally in response to the increase of the mass loading in the range of 100~1000 nMol/L.The modified sensor exhibits a high sensitivity of 677.07 Hz/nMol/L and good selectivity.
作者
郑丹
桂丹
汪宝元
ZHENG Dan;GUI Dan;WANG Bao-yuan(College of Electronic and Engineering,Wuhan Vocational College of Software Engineering,Wuhan 430205,China;College of Physics & Electronic Technology,Hubei University,Wuhan 430062,China;Department of Electronic Science and Technology,Huazhong University of Science and Technology,Wuhan 430074,China)
出处
《仪表技术与传感器》
CSCD
北大核心
2018年第12期42-45,共4页
Instrument Technique and Sensor
基金
国家自然科学基金项目(51502084)
关键词
薄膜体声波谐振器
适配体
汞离子
谐振频率
灵敏度
生物传感器
thin film bulk acoustic resonator
aptamer
mercury iron
resonant frequency
sensitivity
biosensor
