摘要
以学术争鸣和观点述评的方式系统介绍医学3.0与健康管理2.0的观点和内容,通过对近年来因慢病导致死亡的数量远远超过战争所带来的死亡人数的分析和思考,指出慢病防控几乎是人类输得最惨的一场战争。通过对慢病防控这场战争进行反思和总结,结合国内外医学领域(含中医和西医)相关研究,指出以往对慢病起源及其发生发展过程出现的认识不足和失误以及相应的防控策略出现的方向性、战略性错误是导致慢病失控的关键因素,为此,需要重新全面认识慢病起源,并将慢病起源指向生活方式和饮食习惯的失衡所导致的肠道菌群紊乱这个关键点,其中的核心观点即"菌心说"学说认为,肠道菌群而并非大脑摄食中枢是驱动人体产生饥饿感,从而进行摄食的关键原因。为此,基于"饥饿源于菌群"与"慢病源于(肠道菌群向人体传递饥饿感而胁迫人体被动)摄食"所形成的"慢病源于菌群"的新观点,为将中医(医学1.0)和西医(医学2.0)升级到医学3.0阶段提供了科学依据,并顺应性地提出了健康管理2.0的新思路。由于近年来基于该新思路的技术方案已在肥胖、"三高"、荨麻疹、痛经等多种慢病(症状)的改善中陆续得到验证,因此进一步指出可将人体通过"一分为三"的辩证思维方式,理解为与人的三大功能(生物学功能、心理学功能、社会学功能)相对应的"两膜三区"新结构,即血脑屏障(BBB-1)和血菌屏障(BBB-2)这两个生物膜系统以及人体(肉体)、菌群(菌心)和人脑(认知)三个区域,其中肉体以人类基因组操作系统(OS/1)为代码运行,发挥为菌心和人脑提供能量(血糖)的作用,作为支撑菌心和人脑的支撑平台而存在,菌心以人体共生微生物尤其是肠道菌群基因组操作系统(OS/2)为代码运行,赋予人体饥饿感、人体对不同种类食物和数量的客观偏好性以及欲望、情商等依赖于物质的心理相关事件功能活动的物质基础,而人脑则以人类(区别于动物)所特有的语言、文字、符号及其逻辑等以操作系统(OS/3)为代码运行,赋予人类通过思维活动完成对客观世界以及主观世界的认识,从而形成人类的思想、精神、意志、信仰等高级表型和外在表现。由此可见,医学3.0不仅为慢病起源提供了新的认识论和慢病防控的方法论参考,而且对于如何认识人本身,进而认识到自然界的有序性以及人必须按照自然界的有序性而规范自己的言行,从而为确保身心健康提供了参考思路,期待在通过讨论和辩论进行深入论证和实践检验的基础上,促进这些新观点为人、医学以及社会的定义提供新的认识,加速促进健康中国战略的早日实现。
In this paper,we introduced the concept of medical science version 3.0(MS3.0)and health care management version 2.0(HCM2.0).We reviewed and analyzed the number of human death caused by human war and found the death number of human beings caused by the chronic diseases are extremely significant larger than that by the human war,which means that a large failure for the human being losing the war fighting with the chronic diseases(CDs).After carefully summarized the previous studies around the world and based on our own studies coupled with a large number of clinical tests with our own bodies,we finally and unexpectedly found that the gut flora caused CDs in our body.Most of our CDs were caused by improper life styles and unhealthy food and drinking habits,but the key point is that the hunger sensation comes from the gut flora.When normal gut flora was destroyed by improper intake of food and drink,then they will produce a large number of CD-inducing factors and caused the human body to be CD status.In addition,we found when we control the irregular and wrong gut flora,then the CDs will significantly go into good status.Therefore,we developed the new model of Medical Science version(MS3.0)by defining the cause of CDs to be gut flora other than the human genes.The MS3.0 is an easily-to-be-understood updated version of the Traditional Chinese Medicine(TCM)of Medical Science version 1.0(MS1.0)and the Western Medicine of Medical Science version 2.0(MS2.0).In the view of MS3.0,the human body could be divided to be two membranes and three parts.The first membrane is the blood brain barrier(BBB-1)to separate the human brain system from the human blood,while the second membrane is the blood bacteria barrier(BBB-2)to separate the gut flora from the human blood.As for the three parts,the first is the human body itself as a platform to provide the blood for the human brain and the gut flora,while the gut flora is the second part which drive the material needs for the human body,and the human brain is the third part in the body for thinking and talking and communications.The human genomic DNA system(OS/1)is able to support the development of the human body,while the gut flora genomic DNA system(OS/2)aims to support the food needs for the human body,and the human brain system(OS/3)works for thinking by using the human language and words and sentences.This is a full-view of the human body and the gut flora as well as for the human brain.Only when we can now correctly understand and easily control the human is composed of these two membranes and three parts,we will finally win the war fighting with the human CDs lasted for several thousands of years in the whole human history.In conclusion,the MS3.0 and HCM2.0 will open a new window for our human being to have a healthy and happy life in the future far away from the CDs.
作者
张成岗
巩文静
李志慧
高大文
高艳
ZHANG Cheng-Gang;GONG Wen-Jing;LI Zhi-Hui;GAO Da-Wen;GAO Yan(Institute of Radiation Medicine,Academy of Military Medical Sciences,Academy of Military Sciences,Military Cognitive and Mental Health Research Center of PLA,Beijing 100850,China)
出处
《转化医学电子杂志》
2018年第12期108-124,共17页
E-Journal of Translational Medicine
基金
国家重大新药创制项目(2014ZX09J14107-05B,2012ZX09102301-016)
国家自然科学基金项目(81371232,81573251)
国家973计划项目(2012CB518200)
关键词
慢病
慢病起源
慢病防控
慢病失控
菌心学说
摄食
按时吃饭
按需吃饭
肠道菌群优先原则
医学3.0
健康管理2.0
两膜三区
血脑屏障
血菌屏障
运动处方
营养处方
教育处方
医学巨婴
医学批判
有序性
失序性
模拟医学
仿真医学
chronic disease
origin of the chronic disease
prevention and management of chronic disease
loss of control on chronic disease
gut flora-centric theory
eating
eating according to time
eating according to needs
gut flora principle priority
medical science version 3.0
health care management version 2.0
two membranes and three parts model of the human body
blood brain barrier
blood bacteria barrier
exercise prescription
nutrition prescription
educational prescription
fat baby thinking in medical science
medical criticism
in order
disorder
modulation of medical science
simulation of medical science
