摘要
目的:了解地诺前列酮栓(欣普贝生)促宫颈成熟引产过程中出现宫缩过频后不同取药时机对分娩结局的影响。方法:回顾性分析本院使用欣普贝生促宫颈成熟引产患者88例的临床资料。根据发生宫缩过频后的处理结果将其分为立即取药组(立即取出欣普贝生)54例和继续放置组(继续放置至宫颈成熟再取药)34例,比较两组分娩结局。结果:继续放置组的药物放置时长长于立即取药组,放药至分娩时长短于立即取药组,24 h内阴道分娩比例高于立即取药组,剖宫产率低于立即取药组,羊水污染程度轻于立即取药组,比较差异均有统计学意义(P<0.05);两组经阴道分娩的产道及会阴裂伤情况、新生儿体重、入住NICU比例、产后2 h出血量、血红蛋白差值比较,差异均无统计学意义(P>0.05)。结论:欣普贝生促宫颈成熟引产过程中出现宫缩过频时,在严密监测下继续放置直至宫颈成熟再取出欣普贝生,能提高24 h内阴道分娩比例,减少剖宫产,且不增加分娩的母婴并发症。
Objective:To understand the effect of different timing of taking out medicine on outcome of labor after Dinoprostone Suppositories induced labor on the occurrence of uterine tachysystole.Method:The clinical data of 88 cases of cervical ripening induced labor used Dinoprostone Suppositories in our hospital were retrospectively analyzed.According to the results of treatment after uterine contraction overfrequency,they were divided into 54 cases of immediate take out medication group(immediate take out Dinoprostone Suppositories)and 34 cases of continued placement group(continued placement until cervical ripening before taking out medicine).The delivery outcomes of two groups were compared.Result:The drug placement time in continued placement group was longer than that of immediate take out medication group,the medication until delivery time was shorter than that of immediate take out medication group,the proportion of vaginal delivery within 24 h was higher than that of immediate take out medication group,the cesarean section rate was lower than that of immediate take out medication group,the level of amniotic fluid pollution was lighter than that of immediate take out medication group,the differences were statistically significant(P<0.05).The vaginal delivery of birth canal and perineal laceration,neonatal weight,NICU ratio,2 h postpartum hemorrhage and hemoglobin difference in two groups were compared,the differences were not statistically significant(P>0.05).Conclusion:When Dinoprostone Suppositories induced labor to cause uterine tachysystole,continuous placement of drugs under close monitoring until cervical ripeness before removal can increase the proportion of vaginal delivery within 24 hours,reduce cesarean section,and do not increase maternal and infant complications.
作者
童美和
于海微
TONG Meihe;YU Haiwei(Xiamen Hospital of Traditional Chinese Medicine Affiliated to Fujian University of Traditional Chinese Medicine,Xiamen 361009,China)
出处
《中国医学创新》
CAS
2018年第34期42-46,共5页
Medical Innovation of China
关键词
地诺前列酮栓
宫缩过频
引产
取药时机
Dinoprostone Suppositories
Uterine tachysystole
Induced labour
Time of taking medicine
