摘要
目的评价慢性阻塞性肺疾病(简称慢阻肺)患者中抑郁的发生率,并探讨其与肺通气功能、症状及急性加重风险的关系。方法募集2016年10月—2017年9月就诊于郑州人民医院呼吸与危重症医学科的慢阻肺患者124例。对所有受试者均收集人口学资料、完成肺通气功能、抑郁评价,并采用CAT量表、mMRC量表评价慢阻肺患者症状、记录其最近12个月急性加重次数。结果慢阻肺患者合并抑郁的发生率为22.5%。存在抑郁症状的慢阻肺患者与无抑郁症状的患者相比:(1)肺通气功能差异无统计学意义(P> 0.05);(2)CAT评分、mMRC评分均明显增加(28.9±6.2)分vs.(13.7±8.0)分,P <0.05;(3.2±0.5)vs.(1.7±0.9)分,P <0.05;(3)最近12个月急性加重次数明显增加(3.8±1.7)次vs.(0.8±0.3)次,P <0.05。结论合并抑郁症状的慢阻肺患者症状更重,最近12个月急性加重次数更多。
Objective To evaluate the incidence of depression in patients with chronic obstructive pulmonary disease(COPD),and to explore its relationship with pulmonary ventilation function,symptoms and risk of acute exacerbation.Methods 124 COPD patients were recruited from October 2016 to September 2017 in the Department of Respiratory and Critical Care Medicine,Zhengzhou People's Hospital.All subjects collected demographic data,completed pulmonary ventilation function and depression assessment.The symptoms of COPD patients were evaluated by CAT scale and mMRC scale,and the number of acute exacerbations in the last 12 months was recorded.Results The incidence of depression in COPD patients was 22.5%.(1)Compared with patients without depressive symptoms,COPD patients with depressive symptoms had no significant difference in pulmonary ventilation function(P>0.05).(2)CAT score and mMRC score increased significantly(28.9±6.2)vs.(13.7±8.0),P<0.05;(3.2±0.5)vs.(1.7±0.9),P<0.05;(3)In the last 12 months,the number of acute exacerbations increased significantly(3.8±1.7)vs.(0.8±0.3),P<0.05.Conclusion The symptoms of COPD patients with depressive symptoms are more severe,and the number of acute exacerbations in the last 12 months is more.
作者
李增艳
姚菲菲
王富霞
王敏
LI Zengyan;YAO Feifei;WANG Fuxia;WANG Min(Department of Respiratory and Critical Care Medicine,People’s Hospital of Zhengzhou,Zhengzhou He’nan 450003,China)
出处
《中国继续医学教育》
2019年第2期77-79,共3页
China Continuing Medical Education
关键词
肺疾病
慢性阻塞性
抑郁
肺功能
症状
急性加重
pulmonary disease
chronic obstructive disease
depression
pulmonary function
symptoms
acute exacerbation
