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放化疗结合生物靶向治疗乳腺癌效果观察 被引量:2

Observation on Clinical Effect of Radiotherapy and Chemotherapy Combined With Biological Targeting Therapy for Breast Cancer
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摘要 目的探讨放化疗结合生物靶向治疗乳腺癌的临床效果。方法选取2014年6月—2016年6月100例乳腺癌早期改良根治术后患者为研究对象,并将所有患者分为常规组和观察组,每组50例,常规组患者实施改良根治术后实施辅助性治疗,观察组在常规组治疗方式基础上,再联合生物靶向治疗,观察对比其结果。结果两组患者的复发率、生存率及远处转移率对比差异无统计学意义(P> 0.05),但是观察组的生活质量优于常规组,差异有统计学意义(P <0.05)。结论对乳腺癌早期改良根治术后患者实施放化疗联合生物靶向治疗,效果显著,价值颇高。 Objective To explore the clinical effect of radiotherapy and chemotherapy combined with biological targeting therapy for breast cancer.Methods 100 cases of early modified radical mastectomy from June 2014 to June 2016 were selected as the research object,and all the patients were divided into the routine group and the observation group,with 50 cases in each group.The patients in the routine group were treated with modified radical mastectomy,and the observation group was treated with biological target therapy on the basis of the conventional therapy.The results was compared.Results There was no significant difference in recurrence rate,survival rate and distant metastasis rate between the two groups(P>0.05).However,the quality of life in the observation group was better than that in the routine group(P<0.05).Conclusion Radiotherapy and chemotherapy combined with biological targeting therapy for patients with breast cancer after modified radical mastectomy are effective.
作者 朱继敏 王德猛 ZHU Jimin;WANG Demeng(Department of Oncology,457^th Hospital of the Chinese People's Liberation Army,Wuhan Hubei 430010,China)
出处 《中国继续医学教育》 2019年第2期105-107,共3页 China Continuing Medical Education
关键词 乳腺癌早期改良根治术 放化疗 生物靶向治疗 生活质量 生存率 临床效果 early radical mastectomy for breast cancer radiotherapy and chemotherapy biological targeted therapy quality of life survival rate clinical effect
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