摘要
目的探讨急性胰腺炎患者降钙素原(PCT)、D-乳酸及C反应蛋白(CRP)与病情严重程度的相关性。方法选取收治的急性胰腺炎患者100例,按照Ranson评分分组,<3分者为急性轻症胰腺炎组(64例),≥3分为急性重症胰腺炎组(36例);按照APACHFⅡ评分分组,<8分者为急性轻症胰腺炎组(67例),≥8分为急性重症胰腺炎组(33例),检测入院时血清PCT、D-乳酸及CRP水平。结果按照Ranson评分、APACHFⅡ评分分组,急性重症胰腺炎组患者PCT、D-乳酸及CRP水平高于急性轻症胰腺炎组(P<0.05);Spearman相关分析,PCT、D-乳酸及CRP与病情严重程度Ranson与APACHFⅡ评分间有正相关性(P<0.05),PCT与D-乳酸及CRP间有正相关性(r=0.71、r=0.63,P<0.05),D-乳酸与CRP间有正相关性(P<0.05)。结论急性胰腺炎患者PCT、D-乳酸及CRP水平与病情严重程度密切相关,可用于病情严重程度的评估。
Objective To investigate the calcitonin original(PCT)in patients with acute pancreatitis,D-lactic acid and c-reactive protein(CRP)and the correlation of illness severity.Methods Select treated 100 cases of patients with acute pancreatitis,according to the grouping Ranson score<3 points for acute mild pancreatitis group(64 cases),3 or more divided into acute severe pancreatitis group(36 cases),according to the grouping APACHFⅡscore<8 points for acute mild pancreatitis group(67 cases),8 or more divided into acute severe pancreatitis group(33 cases),detection of serum PCT on admission,D-lactic acid and CRP level.Results According to the Ranson score,APACHFⅡscore group,all patients with severe acute pancreatitis group of PCT,D-lactic acid and CRP levels higher than in acute mild pancreatitis group(P<0.05);Spearman correlation analysis,lactic acid and CRP and PCT,D-the illness severity Ranson and has a positive correlation between APACHFⅡscore(P<0.05),PCT lactic acid and has a positive correlation between CRP and D-(r=0.71,r=0.63,P<0.05),D-lactic acid and has a positive correlation between CRP(P<0.05).Conclusion PCT in patients with acute pancreatitis,D-lactic acid and CRP levels are closely associated with disease severity,can be used for assessment of disease severity.
作者
罗大林
杭锦玲
李丹
Luo Dalin;Hang Jinlin;Li Dan(Hospital southeast of Chongqing,Chongqing,401336,China)
出处
《当代医学》
2019年第4期93-95,共3页
Contemporary Medicine
