摘要
目的:评价丹红对冠心病血液流变学的影响。方法:通过检索数据库,收集关于丹红治疗冠心病随机对照试验的文献,比较丹红与对照组血液流变学指标的变化,采用Revman5.3软件进行Meta分析和TSA分析。结果:Meta分析显示,丹红组能明显降低全血高切黏度[OR=-1.16,95%CI(-1.51,-0.80)]、全血低切粘度[OR=-1.73,95%CI(-2.35,-1.10)]、血浆黏度[OR=-32,95%CI(-47,-0.18]、红细胞容积[OR=-3.07,95%CI(-3.91,-2.23)]、纤维蛋白原水平[OR=-0.87,95%CI(-1.12,-0.62)],并且检索文献的病例数均超过TSA值。结论:从现有临床证据来看,丹红治疗CHD优于常规治疗组、丹参和脉络宁组。
Objective:To evaluate Danhong effect on hemorheology of coronary artery disease.Methods:Through the database retrieval,collected about the document of Danhong randomized controlled trials for coronary heart disease,is Danhong with control group in the change of hemorheology indexes,using Revman5.3 Meta analysis software and the TSA sequential analysis.Results:The Meta analysis showed,the experimental group can obviously decrease the whole blood high shear viscosity[(OR=-1.16,95%CI(-1.51,-0.80)],whole blood low shear viscosity[(OR=-1.73,95%CI(-2.35,-1.10)],blood plasma viscosity[OR=32,95%CI(-47,-0.18)],red blood cell volume[(OR=-3.07,95%CI(-3.91,-2.23)],fibrinogen level[(OR=-0.87,95%CI(-1.12,-0.62)],and test cases are more than the TSA.Conclusion:From the point of current clinical evidence,Danhong treatment is superior to the conventional treatment group,salvia miltiorrhiza and context.
作者
江继涛
王勇
胡秀萍
Jiang Jitao;Wang Yong;Hu Xiuping(The First People's Hospital of Chuzhou,Chuzhou 239200,China)
出处
《甘肃医药》
2018年第11期961-964,970,共5页
Gansu Medical Journal
