摘要
目的探讨在常规综合治疗基础上加用银杏蜜环口服溶液辅助治疗进展性缺血性脑卒中(progressive ischemic stroke,PIS)的临床疗效。方法收集PIS患者120例,随机分为治疗组及对照组,每组各60例。对照组给予常规综合治疗,包括抗血小板聚集、调脂稳定斑块、清除氧自由基、活血化瘀等,治疗组在对照组基础上加用银杏蜜环口服溶液10mL·次-1、3次·d-1口服治疗,2组疗程均为2周。对2组患者治疗前,治疗1、2周后神经功能缺损情况采用美国国立卫生研究院脑梗死量表(National Institute of Health Stroke Scal,NIHSS)、日常生活能力量表-巴塞尔指数(Barthel Index,Barthel指数)进行评价,并监测不良反应发生情况。结果治疗1、2周后,2组患者神经功能缺损、日常生活能力均较治疗前改善,但治疗组比对照组改善效果更佳,且疗程2周改善更明显(均P<0.05)。结论在常规综合治疗基础上加用银杏蜜环口服溶液可有效改善PIS患者神经功能缺损、日常生活能力,且随疗程延长,改善越明显。
Objective To investigate the clinical effect of Yinxing Mihuan oral solution on progressive ischemic stroke(PIS).Methods A total of 120 PIS patients were randomly divided into treatment group and control group,with 60 patients in each group.Both groups received routine comprehensive treatment,including inhibiting platelet aggregation,regulating plaque stabilization,scavenging oxygen free radicals,promoting circulation and removing stasis.Additionally,the treatment group was given 10 mL Yinxing Mihuan oral solution 3 times per day.The course of treatment was 2 weeks.Neurological impairment and activities of daily living were assessed using National Institutes of Health Stroke Scale(NIHSS)and Barthel Index,respectively.Results The treatment significantly improved nerve functions and activities of daily living in both groups in a time-dependent manner,and the improvement in treatment group was more obvious than that in control group(P<0.05).Conclusion Conventional comprehensive treatment combined with Yinxing Mihuan oral solution can effectively improve nerve functions and activities of daily living in a time-dependent manner in patients with PIS.
作者
何敏
刘志强
蒋玲霞
朱晓钢
HE Min;LIU Zhi-qiang;JIANG Ling-xia;ZHU Xiao-gang(The Second Department of Neurology,Jiangxi Provincial People's Hospital,Nanchang 330006,China)
出处
《实用临床医学（江西）》
CAS
2018年第11期17-19,32,共4页
Practical Clinical Medicine
