摘要
目的探讨2型糖尿病予以沙格列汀及二甲双胍治疗的疗效、安全性及用药依从性。方法 60例2型糖尿病患者,随机分为对照组及观察组,各30例。对照组使用二甲双胍治疗,观察组使用沙格列汀治疗。比较两组临床疗效、不良事件发生情况、用药依从性。结果观察组总有效率为96.67%,高于对照组的76.67%,差异具有统计学意义(P<0.05)。观察组不良事件发生率为6.67%,低于对照组的20.00%,差异无统计学意义(P>0.05)。观察组总依从率为100.00%,高于对照组的80.00%,差异具有统计学意义(P<0.05)。结论在2型糖尿病治疗方面,相比二甲双胍,沙格列汀应用效果及用药依从性更优。
Objective To discuss the efficacy,safety and drug compliance of shagretine and melbine in the treatment of type 2 diabetic mellitus.Methods A total of 60 type 2 diabetic mellitus patients were randomly divided into control group and observation group,with 30 cases in each group.The control group was treated with melbine,and the observation group was treated with shagretine.Comparison were made on clinical efficacy,occurrence of adverse events and drug compliance between the two groups.Results The observation group had higher total effective rate as 96.67%than 76.67%in the control group,and the difference was statistically significant(P<0.05).The observation group had lower incidence of adverse events as 6.67%than 20.00%in the control group,but the difference was not statistically significant(P >0.05).The observation group had higher total compliance rate as 100.00%than 80.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion Compared with melbine,shagretine shows better application effect and drug compliance in treating type 2 diabetic mellitus.
作者
杨贺
YANG He(Shenyang Shenhe District Diabetes Treatment Center,Shenyang 110010,China)
出处
《中国现代药物应用》
2019年第2期94-95,共2页
Chinese Journal of Modern Drug Application
