摘要
癌症基因组研究在癌症的预防、诊断和治疗方面有着广阔的前景,但同时也存在诸多伦理、法律和社会问题。知情同意程序被视为研究者与参与者沟通和建立信任的独特机会,确保参与者做出合理的决定。通过重新思考癌症基因组研究中知情同意五要素的内涵,包括信息披露的内容、表意能力的评估、促进理解的方法、自愿的本质及同意的四种实践模式,提出优化策略和建议,从而在有效保障潜在参与者权益的前提下,促进癌症基因组研究的长远发展。
Although cancer genomic research has broad prospects on cancer prevention,diagnosis and treatment,there are still many ethical,legal,and social issues.The informed consent process is considered as a unique opportunity for researchers to communicate and build trust with participants,ensuring that participants can make informed decisions.This article reconsiders the connotations of the five elements of informed consent in cancer genomic research,including content of disclosure,assessment of competency,ways to promote understanding,nature of voluntariness and four practice patterns of consent.In addition,optimized strategies and recommendations are also put forward in this article.In this way,the long-term development of cancer genomic research can be promoted on the premise of effectively protecting the rights of potential participants.
作者
李梦璐
杨艳
方兰
汪秋伊
王蕾
许良梅
谢伦芳
LI Meng-lu;YANG Yan;FANG Lan(School of Nursing,Anhui Medical University,Hefei 230032,China)
出处
《医学与哲学》
2019年第3期34-37,共4页
Medicine and Philosophy
基金
2017年安徽省高等学校人文社会科学研究重点项目(SK2017A0167)
关键词
基因组研究
知情同意
信息披露
表意能力
充分理解
自愿
genomic research
informed consent
disclosure
competency
understanding
voluntariness
