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南方部分农村地区人群蓝氏贾第鞭毛虫疾病负担研究

Giardiasis burden of disease in part of the southern rural areas of China
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摘要 目的了解我国南方部分地区人群蓝氏贾第鞭毛虫疾病负担。方法采用多阶段随机抽样方法分别从我国湖北和广西某市各抽取约2000人作为调查对象,同时收集乡镇和县市级医院2014年10-12月门诊腹泻患者。利用碘液染色法检测粪便中贾第虫包囊,通过问卷调查收集调查对象一般人口学资料、就诊情况和疾病的社会经济影响等信息。结果一般人群和腹泻患者贾第虫感染率分别为1.72%(69/4015)和5.17%(20/387);按照地区、年龄、性别分组后的不同人群贾第虫感染率差别均无统计学意义(P>0.05)。贾第虫在湖北和广西地区DALYs分别为0.04029/千人和0.02783/千人。门诊腹泻患者中贾第虫感染者每次人均经济负担为140.81元,主要为直接经济负担。结论反映流行病学负担的贾第虫感染率和DALYs总体较低,但贾第虫病疾病经济负担较高,疾病防控应该在重点人群,预防为主,降低疾病负担。 To evaluate the disease burden of giardiasis among residents in southern areas of China,multistage sampling method was used.The 2 000 people were selected from city in Hubei and Guangxi provinces respectively.The out-patients with diarrhea attending township,county and municipal hospitals from October to December in 2014 were also selected.Faecal samples were collected and Giardia cysts in feces were detected by iodine staining methods.General demographic information,social and economic impact of the disease and other information were collected through questionnaires.The burden of disease was calculated in the form of disability-adjusted life years(DALYs).The infection rate in the general population was 1.72%(69/4 015)while the infection rate in diarrheic patients was 5.17%(20/387).There was no significant difference among different groups after being grouped by region,age and sex(P > 0.05).DALYs were 0.040 29/1 000 persons and 0.027 83/1 000 persons in Hubei and Guangxi respectively.The average economic burden per case was CNY140.81,which was mainly from the direct economic cost.Giardia infection rates and DALYs are generally low,but giardiasis has a higher economic burden.And disease prevention and control should focus on the key population to reduce the burden of disease.
作者 王丽 夏云婷 田向红 何祖安 钟格梅 张荣 WANG Li;XIA Yun-ting;TIAN Xiang-hong;HE Zu-an;ZHONG Ge-mei;ZHANG Rong(National Center for Rural Water Supply Technical Guidance,Chinese Centerfor Disease Control and Prevention,Beijing 102200,China;Hubei Province Center For Disease Control and Prevention,Wuhan 430079,China;Guangxi Center For Disease Control and Prevention,Nanning 530028,China)
出处 《中国人兽共患病学报》 CAS CSCD 北大核心 2019年第1期34-38,共5页 Chinese Journal of Zoonoses
基金 国家卫生和计划生育委员会公益性行业科研专项(No.201302004)~~
关键词 贾第鞭毛虫 感染率 疾病负担 Giardia infection rate burden of disease
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