摘要
目的观察安神促眠方联合调督安神针法对围绝经期心肾不交型失眠的改善及性激素水平的影响。方法将94例围绝经期心肾不交型失眠患者按照随机数字表法分为2组。对照组47例予安神促眠方治疗,治疗组47例在对照组治疗基础上加调督安神针法治疗。2组均治疗4周后统计疗效,比较2组治疗前后匹兹堡睡眠质量指数(PSQI)评分、围绝经期综合征生活质量评定量表(MENQOL)评分、中医证候评分及血清雌二醇(E2)、卵泡刺激素(FSH)、黄体生成激素(LH)水平变化。结果治疗组总有效率89. 36%,对照组总有效率72. 34%,治疗组总有效率高于对照组(P <0. 05)。治疗后,2组PSQI各项评分及总分均较本组治疗前降低(P <0. 05),且治疗组睡眠质量、睡眠时间、睡眠障碍、日间功能评分及总分均低于对照组治疗后(P <0. 05)。2组治疗后MENQOL评分及中医证候评分均较本组治疗前降低(P <0. 05),且治疗组低于对照组(P <0. 05)。2组治疗后E2水平均较本组治疗前升高(P <0. 05),FSH和LH水平降低(P <0. 05),且治疗组E2水平高于对照组(P <0. 05),FSH和LH水平低于对照组(P <0. 05)。结论安神促眠方联合调督安神针法治疗围绝经期心肾不交型失眠疗效显著,可调节激素水平,改善失眠症状,提高患者生活质量。
Objective To observe the effects of Anshen Cumian prescription combined with Tiaodu Anshen acupuncture on the improvement of perimenopausal insomnia of heart-kidney imbalance type and the effect of sex hormone level.Methods 94 patients with perimenopausal insomnia of heart-kidney imbalance type were divided into two groups according to the random number table method.47 cases in control group were treated by Anshen Cumian prescription.47 cases in treatment group were treated by Tiaodu Anshen acupuncture on the basis of the control group.The curative effect was evaluated after 4 weeks of treatment in both groups.The changes of Pittsburgh sleep quality index(PSQI)score,perimenopausal syndrome quality of life rating scale(MENQOL)score,TCM syndrome score and serum estradiol(E 2),follicle stimulating hormone(FSH),luteinizing hormone(LH)before and after treatment were compared between the two groups.Results The total effective rate was 89.36%in treatment group and 72.34%in control group.The total effective rate of the treatment group was higher than that of the control group(P<0.05).After treatment,the each item scores and total scores of PSQI in the two groups were lower than those in the group before treatment(P<0.05),and the sleep quality,sleep time,sleep disturbance,daytime function score and total score of the treatment group were lower than those of the control group(P<0.05).After treatment,the MENQOL scores and TCM syndrome scores of the two groups were lower than those in the group before treatment(P<0.05),and the treatment group was lower than the control group(P<0.05).After treatment,E 2 levels in both groups were higher than those in the group before treatment(P<0.05),FSH and LH levels were decreased(P<0.05),and E 2 levels in treatment group were higher than those in the control group(P<0.05),FSH and LH levels were lower than those in the control group(P<0.05).Conclusion Anshen Cumian prescription combined with Tiaodu Anshen acupuncture is effective in treating perimenopausal insomnia of heart-kidney imbalance type.It can regulate hormone levels,improve insomnia symptoms and improve the quality of life of patients.
作者
关慧泉
刘宇
GUAN Huiquan;LIU Yu(Clinic of Traditional Chinese Medicine,Beijing Xuanwu Hospital of Traditional Chinese Medicine,Beijing 100050)
出处
《河北中医》
2019年第1期21-25,共5页
Hebei Journal of Traditional Chinese Medicine
基金
北京市科学技术研究与发展计划项目(编号:2015YS001183)
关键词
入睡和睡眠障碍
围绝经期
心肾不交
针刺疗法
中药疗法
Sleep initiation and maintenance disorders
Perimenopause
Heart-kidney imbalance
Acupuncture therapy
Chinese medicine therapy
