摘要
胃癌是我国常见消化道恶性肿瘤之一,且发病率和病死率高,其发病复杂、涉及多因素、呈多阶段、但确切机制尚不明了。随着对胃癌分子生物学研究的不断深入,表观遗传调控所发挥的重要作用已逐渐被人们认识,其主要研究方向包括DNA甲基化、组蛋白修饰、非编码RNA调控等。
Gastric cancer is one of the most common malignant tumors in the digestive tract,and its morbidity and mortality are high. Gastric cancer is a multifactorial,multistage disease,but its exact pathogenesis is still unclear. With deep research on gastric cancer,the important role of epigenetic changes in the pathogenesis of gastric cancer has been gradually recognized,and the research contents mainly include DNA methylation,histone modification,non-coding RNA regulation and so on.
作者
陈薇
张雷
CHEN Wei;ZHANG Lei(Dali University,Dali,Yunnan 671000,China)
出处
《实用医药杂志》
2019年第2期172-176,共5页
Practical Journal of Medicine & Pharmacy
基金
国家自然科学基金项目(No.81560096)
