摘要
目的:观察小柴胡汤加减联合强的松治疗亚急性甲状腺炎的安全性和疗效,为临床治疗提供依据。方法:56例亚急性甲状腺炎患者被随机分为对照组和观察组,每组各28例。两组均口服强的松片;观察组予联合小柴胡汤加减,观察8周。对比分析两组的中医症状积分、临床疗效、实验室检验指标以及不良反应的发生情况。结果:两组接受治疗后,中医症状积分、血清C反应蛋白和ESR水平均较治疗前明显降低,观察组改善更明显(P <0.05)。观察组的治疗总有效率(92.8%)明显高于对照组(67.9%),但总不良反应发生率比对照组低(P <0.05)。结论:小柴胡汤加减联合强的松治疗亚急性甲状腺炎的临床疗效显著,安全性高,值得在临床工作中推广。
Objective:To investigate the safety and efficacy of the Xiaochaihu decoction(小柴胡汤加减)plus prednisone on subacute thyroiditis,and provide the basis for clinical treatment.Methods:56 patients were divided into the observation group(28 patients)and control group(28 patients).Both groups were administered with prednisone.The observation group was treated with the Xiaochaihu decoction more.The symptom integral,clinical effects,laboratory parameters and adverse reactions between two groups were compared and analyzed.Results:After treatment,the symptom integral,serum CRP and ESR were significantly decreased;those in the observation group were improved more obviously(P<0.05).The total efficiency in the observation group was 92.8%,significantly higher than 67.9%in the control group.And the adverse reaction rate in the observation group was lower than the control group(P<0.05).Conclusion:The Xiaochaihu decoction plus prednisone on subacute thyroiditis shows an obvious effect,with high safety,is worthy of recommendation in the clinical work.
出处
《中医临床研究》
2019年第1期47-49,共3页
Clinical Journal Of Chinese Medicine
关键词
小柴胡汤
强的松
亚急性甲状腺炎
疗效观察
The Xiaochaihu decoction
Prednisone
Subacute thyroiditis
Effective observation
