摘要
目的分析贵阳市某三甲医院体检人群高尿酸血症(HUA)检出情况。方法 2017年3月—2018年3月在贵阳市某三甲医院体检中心参加体检且体检资料完整者共计12 771例,其中男7 261例,女5 510例。收集整理体检人员各项体检指标数据,分析HUA和各因素之间的相关性。结果 HUA患病率为24. 63%(3 146/12 771),其中男性HUA患病率32. 46%(2 357/7 261),女性HUA患病率14. 32%(789/5 510)。多因素非条件Logistic回归分析表明女性(OR=0. 512,P <0. 001)、高密度脂蛋白胆固醇(OR=0. 822,P <0. 001)是HUA的保护因素;高体质量指数(OR=1. 583,P <0. 001)、高血压(OR=1. 292,P <0. 001)、高血清总胆固醇(OR=1. 118,P=0. 002)、高甘油三酯(OR=2. 135,P <0. 001)、高丙氨酸氨基转移酶(OR=1. 302,P <0. 001)、高天门冬氨酸氨基转移酶(OR=1. 628,P <0. 001)、高尿素(OR=1. 147,P=0. 008)是HUA的危险因素。结论贵阳市体检人群HUA患病率较高,且有年轻化趋势,应高度关注贵阳市年轻人群的血尿酸水平。
Objective To investigate the prevalence and risk factors of hyperuricemia(HUA)among people undergoing physical examination group in a grade-A tertiary hospital in Guiyang.Methods Totally 12771 persons(7261 male subjects and 5510 female subjects)who participated in physical examination from March 2017 to March 2018 in the physical examination center of a grade-A tertiary hospital in Guiyang were included as the research objects.The data of physical examination indicators were collected and the relationship between HUA and influencing factors was analyzed.Results The prevalence of HUA was 24.63%(3146/12771),and was 32.46%(2357/7261)in male subjects and 14.32%(789/5 510)in female subjects.Multivariate unconditional logistic regression analysis showed that female(OR=0.512,P<0.001)and high density lipoprotein cholesterol(OR=0.822,P<0.001)were protective factors of HUA;high body mass index(OR=1.583,P<0.001),hypertension(OR=1.292,P<0.001),high serum total cholesterol(R=1.118,P=0.002),high triglyceride(OR=2.135,P<0.001),high glutamic alanine aminotransferase(OR=1.302,P<0.001),high glutamic oxaloacetate aminotransferase(OR=1.628,P<0.001),and high urine(OR=1.147,P=0.008)were risk factors of HUA.Conclusions There was a relatively high prevalence of HUA among people undergoing physical examination group in a grade-A tertiary hospital in Guiyang.More efforts should be paid to monitor the level of serum uric acid among young people in Guiyang.
作者
张家耀
肖丽娜
董倩倩
迟宇
ZHANG Jiayao;XIAO Lina;DONG Qianqian;CHI Yu(Guiyang College of Traditional Chinese Medicine,Guiyang,Guizhou,550003;Department of Nursing,Second Affiliated Hospital of Guiyang College of Traditional Chinese Medicine,Guiyang,Guizhou,550003;Physical Examination Center,Second Affiliated Hospital of Guiyang College of Traditional Chinese Medicine,Guiyang,Guizhou,550003)
出处
《中西医结合护理（中英文）》
2019年第1期5-8,共4页
Journal of Clinical Nursing in Practice
基金
国家中医药管理局中医药重点学科建设项目-中医护理学(2016-415-000002-08)
关键词
高尿酸血症
体检
患病率
危险因素
高密度脂蛋白胆固醇
体质量指数
hyperuricemia
physical examination
prevalence
risk factors
high-density lipoprotein cholesterol
body mass index
